Angela Thistlethwaite
Overview
Explore the profile of Angela Thistlethwaite including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
224
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0
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Recent Articles
1.
Jones R, Ramirez-Bencomo F, Whiting G, Fang M, Lavender H, Kurzyp K, et al.
PLoS Pathog
. 2024 Nov;
20(11):e1012688.
PMID: 39541395
Gonorrhoea, caused by Neisseria gonorrhoeae, is a common sexually transmitted infection. Increasing multi-drug resistance and the impact of asymptomatic infections on sexual and reproductive health underline the need for an...
2.
Stejskal L, Thistlethwaite A, Ramirez-Bencomo F, Rashmi S, Harrison O, Feavers I, et al.
Nat Commun
. 2024 Aug;
15(1):6712.
PMID: 39112489
Development of a vaccine against gonorrhoea is a global priority, driven by the rise in antibiotic resistance. Although Neisseria gonorrhoeae (Ng) infection does not induce substantial protective immunity, highly exposed...
3.
Aston-Deaville S, Carlsson E, Saleem M, Thistlethwaite A, Chan H, Maharjan S, et al.
Vaccine
. 2020 Mar;
38(16):3201-3209.
PMID: 32178907
Neisseria meningitidis is the causative agent of meningococcal meningitis and sepsis and remains a significant public health problem in many countries. Efforts to develop a comprehensive vaccine against serogroup B...
4.
Austerberry J, Thistlethwaite A, Fisher K, Golovanov A, Pluen A, Esfandiary R, et al.
Biochemistry
. 2019 Jul;
58(32):3413-3421.
PMID: 31314511
Increased protein solubility is known to correlate with an increase in the proportion of lysine over arginine residues. Previous work has shown that the aggregation propensity of a single-chain variable...
5.
Salleh M, Karuppiah V, Snee M, Thistlethwaite A, Levy C, Knight D, et al.
mBio
. 2019 Jun;
10(3).
PMID: 31186316
Natural competence is the term used to describe the uptake of "naked" extracellular DNA by bacteria; it plays a significant role in horizontal genetic exchange. It is associated with type...
6.
Eyes T, Austerberry J, Dearman R, Johannissen L, Kimber I, Smith N, et al.
Mol Immunol
. 2018 Dec;
105:181-189.
PMID: 30550980
Aggregation of therapeutic proteins is a key factor in the generation of unwanted immunogenicity, and can result in reduced serum half-life, neutralization of function and adverse health effects. There is...
7.
Collins R, Karuppiah V, Siebert C, Dajani R, Thistlethwaite A, Derrick J
Sci Rep
. 2018 Sep;
8(1):14022.
PMID: 30232337
Type IV pili are responsible for a diverse range of functions, including twitching motility and cell adhesion. Assembly of the pilus fiber is driven by a cytoplasmic ATPase: it interacts...
8.
Karuppiah V, Thistlethwaite A, Derrick J
J Struct Biol
. 2016 Sep;
196(3):375-384.
PMID: 27612581
Type IV pilins are proteins which form polymers that extend from the surface of the bacterial cell; they are involved in mediating a wide variety of functions, including adhesion, motility...
9.
Karuppiah V, Thistlethwaite A, Dajani R, Warwicker J, Derrick J
J Biol Chem
. 2014 Oct;
289(48):33187-97.
PMID: 25313401
CinA is a widely distributed protein in Gram-positive and Gram-negative bacteria. It is associated with natural competence and is proposed to have a function as an enzyme participating in the...
10.
Karuppiah V, Collins R, Thistlethwaite A, Gao Y, Derrick J
Proc Natl Acad Sci U S A
. 2013 Nov;
110(48):E4638-47.
PMID: 24218553
Type IV pili are long fibers that are assembled by polymerization of a major pilin protein in the periplasm of a wide range of bacteria and archaea. They play crucial...