Richard F Collins
Overview
Explore the profile of Richard F Collins including associated specialties, affiliations and a list of published articles.
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60
Citations
2075
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Recent Articles
1.
Safavian D, Kim M, Xie H, El-Zeiry M, Palander O, Dai L, et al.
J Cell Biol
. 2023 Mar;
222(4).
PMID: 36912772
Septins are filamentous GTPases that play important but poorly characterized roles in ciliogenesis. Here, we show that SEPTIN9 regulates RhoA signaling at the base of cilia by binding and activating...
2.
Barbieri A, Thonghin N, Shafi T, Prince S, Collins R, Ford R
Membranes (Basel)
. 2021 Dec;
11(12).
PMID: 34940424
ABCB1/P-glycoprotein is an ATP binding cassette transporter that is involved in the clearance of xenobiotics, and it affects the disposition of many drugs in the body. Conformational flexibility of the...
3.
Palander O, Lam A, Collins R, Moraes T, Trimble W
J Biol Chem
. 2021 Apr;
296:100680.
PMID: 33872598
Primary cilia are hubs for several signaling pathways, and disruption in cilia function and formation leads to a range of diseases collectively known as ciliopathies. Both ciliogenesis and cilia maintenance...
4.
Soroor F, Kim M, Palander O, Balachandran Y, Collins R, Benlekbir S, et al.
Mol Biol Cell
. 2020 Dec;
32(3):289-300.
PMID: 33263440
Septins are conserved GTP-binding cytoskeletal proteins that polymerize into filaments by end-to-end joining of hetero-oligomeric complexes. In human cells, both hexamers and octamers exist, and crystallography studies predicted the order...
5.
Mylvaganam S, Riedl M, Vega A, Collins R, Jaqaman K, Grinstein S, et al.
Cell Rep
. 2020 Jun;
31(12):107798.
PMID: 32579925
Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient...
6.
Aston-Deaville S, Carlsson E, Saleem M, Thistlethwaite A, Chan H, Maharjan S, et al.
Vaccine
. 2020 Mar;
38(16):3201-3209.
PMID: 32178907
Neisseria meningitidis is the causative agent of meningococcal meningitis and sepsis and remains a significant public health problem in many countries. Efforts to develop a comprehensive vaccine against serogroup B...
7.
Freeman S, Uderhardt S, Saric A, Collins R, Buckley C, Mylvaganam S, et al.
Science
. 2019 Dec;
367(6475):301-305.
PMID: 31806695
Despite ongoing (macro)pinocytosis of extracellular fluid, the volume of the endocytic pathway remains unchanged. To investigate the underlying mechanism, we used high-resolution video imaging to analyze the fate of macropinosomes...
8.
Ridley C, Lockhart-Cairns M, Collins R, Jowitt T, Subramani D, Kesimer M, et al.
J Biol Chem
. 2019 Oct;
294(45):17105-17116.
PMID: 31570524
Mucin 5B (MUC5B) has an essential role in mucociliary clearance that protects the pulmonary airways. Accordingly, knowledge of MUC5B structure and its interactions with itself and other proteins is critical...
9.
Marques P, Nyegaard S, Collins R, Troise F, Freeman S, Trimble W, et al.
Dev Cell
. 2019 Jun;
50(3):283-295.e5.
PMID: 31231038
Scavenger receptor B1 (SR-B1), the main receptor for high-density lipoprotein (HDL), is key in preventing atherosclerosis. It removes cholesterol from HDL, returning the lipid-poor lipoprotein to the circulation. To study...
10.
Thonghin N, Collins R, Barbieri A, Shafi T, Siebert A, Ford R
BMC Struct Biol
. 2018 Dec;
18(1):17.
PMID: 30545335
Background: P-glycoprotein (ABCB1) is an ATP-binding cassette transporter that plays an important role in the clearance of drugs and xenobiotics and is associated with multi-drug resistance in cancer. Although several...