Jennifer Hesson
Overview
Explore the profile of Jennifer Hesson including associated specialties, affiliations and a list of published articles.
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15
Citations
1107
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0
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Recent Articles
1.
Cavanaugh C, Hesson J, Mathieu J
Methods Mol Biol
. 2023 Dec;
2735:129-143.
PMID: 38038847
Recent advances in patient-derived induced Pluripotent Stem Cell (iPSC) generation, improvement of cardiomyocyte-directed differentiation protocols, and the availability of new genome editing techniques have opened up new avenues for disease...
2.
Ware C, Jonlin E, Anderson D, Cavanaugh C, Hesson J, Sidhu S, et al.
Stem Cell Rev Rep
. 2023 Sep;
19(8):2980-2990.
PMID: 37702917
Embryonic development is a continuum in vivo. Transcriptional analysis can separate established human embryonic stem cells (hESC) into at least four distinct developmental pluripotent stages, two naïve and two primed,...
3.
Smith A, Luttrell S, Dupont J, Gray K, Lih D, Fleming J, et al.
J Tissue Eng
. 2022 Sep;
13:20417314221122127.
PMID: 36082311
Engineered muscle tissues represent powerful tools for examining tissue level contractile properties of skeletal muscle. However, limitations in the throughput associated with standard analysis methods limit their utility for longitudinal...
4.
Smith A, Kim J, Chun C, Gharai A, Moon H, Kim E, et al.
Adv Biol (Weinh)
. 2021 Dec;
6(2):e2101308.
PMID: 34958183
Charcot-Marie-Tooth disease type 2D (CMT2D), is a hereditary peripheral neuropathy caused by mutations in the gene encoding glycyl-tRNA synthetase (GARS1). Here, human induced pluripotent stem cell (hiPSC)-based models of CMT2D...
5.
Smith A, Chun C, Hesson J, Mathieu J, Valdmanis P, Mack D, et al.
Front Cell Dev Biol
. 2021 Oct;
9:728707.
PMID: 34660586
Gene editing technologies hold great potential to enhance our ability to model inheritable neurodegenerative diseases. Specifically, engineering multiple amyotrophic lateral sclerosis (ALS) mutations into isogenic cell populations facilitates determination of...
6.
Kim H, Yardimci G, Bonora G, Ramani V, Liu J, Qiu R, et al.
PLoS Comput Biol
. 2020 Sep;
16(9):e1008173.
PMID: 32946435
Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization. However, the extremely sparse nature of scHi-C data poses a significant...
7.
Yang W, Lampe P, Kensel-Hammes P, Hesson J, Ware C, Crisa L, et al.
iScience
. 2019 Aug;
19:450-460.
PMID: 31430690
Efficient stem cell differentiation into pancreatic islet cells is of critical importance for the development of cell replacement therapies for diabetes. Here, we identify the expression pattern of connexin 43...
8.
Battle S, Jayavelu N, Azad R, Hesson J, Ahmed F, Overbey E, et al.
Stem Cell Reports
. 2019 May;
12(5):1129-1144.
PMID: 31056477
During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data...
9.
Ma W, Ay F, Lee C, Gulsoy G, Deng X, Cook S, et al.
Methods
. 2018 Feb;
142:59-73.
PMID: 29382556
The folding and three-dimensional (3D) organization of chromatin in the nucleus critically impacts genome function. The past decade has witnessed rapid advances in genomic tools for delineating 3D genome architecture....
10.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, et al.
Nat Cell Biol
. 2015 Nov;
17(12):1523-35.
PMID: 26571212
For nearly a century developmental biologists have recognized that cells from embryos can differ in their potential to differentiate into distinct cell types. Recently, it has been recognized that embryonic...