Carol B Ware
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Explore the profile of Carol B Ware including associated specialties, affiliations and a list of published articles.
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2826
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Recent Articles
1.
Ware C, Jonlin E, Anderson D, Cavanaugh C, Hesson J, Sidhu S, et al.
Stem Cell Rev Rep
. 2023 Sep;
19(8):2980-2990.
PMID: 37702917
Embryonic development is a continuum in vivo. Transcriptional analysis can separate established human embryonic stem cells (hESC) into at least four distinct developmental pluripotent stages, two naïve and two primed,...
2.
Kim H, Yardimci G, Bonora G, Ramani V, Liu J, Qiu R, et al.
PLoS Comput Biol
. 2020 Sep;
16(9):e1008173.
PMID: 32946435
Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization. However, the extremely sparse nature of scHi-C data poses a significant...
3.
Hussein A, Wang Y, Mathieu J, Margaretha L, Song C, Jones D, et al.
Dev Cell
. 2020 Jan;
52(2):236-250.e7.
PMID: 31991105
Regulation of embryonic diapause, dormancy that interrupts the tight connection between developmental stage and time, is still poorly understood. Here, we characterize the transcriptional and metabolite profiles of mouse diapause...
4.
Yang W, Lampe P, Kensel-Hammes P, Hesson J, Ware C, Crisa L, et al.
iScience
. 2019 Aug;
19:450-460.
PMID: 31430690
Efficient stem cell differentiation into pancreatic islet cells is of critical importance for the development of cell replacement therapies for diabetes. Here, we identify the expression pattern of connexin 43...
5.
Battle S, Jayavelu N, Azad R, Hesson J, Ahmed F, Overbey E, et al.
Stem Cell Reports
. 2019 May;
12(5):1129-1144.
PMID: 31056477
During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data...
6.
Ma W, Ay F, Lee C, Gulsoy G, Deng X, Cook S, et al.
Methods
. 2018 Feb;
142:59-73.
PMID: 29382556
The folding and three-dimensional (3D) organization of chromatin in the nucleus critically impacts genome function. The past decade has witnessed rapid advances in genomic tools for delineating 3D genome architecture....
7.
Choi M, Genereux D, Goodson J, Al-Azzawi H, Allain S, Simon N, et al.
PLoS Genet
. 2017 Nov;
13(11):e1007060.
PMID: 29107996
In storing and transmitting epigenetic information, organisms must balance the need to maintain information about past conditions with the capacity to respond to information in their current and future environments....
8.
Ware C
Stem Cells
. 2016 Sep;
35(1):35-41.
PMID: 27663171
The naïve state of pluripotency is actively being explored by a number of labs. There is some controversy in the field as to the true identity of naïve human pluripotent...
9.
Borges G, Vencio E, Quek S, Chen A, Salvanha D, Vencio R, et al.
J Cell Physiol
. 2016 Jan;
231(9):2040-7.
PMID: 26773436
The lineage relationship between prostate adenocarcinoma and small cell carcinoma was studied by using the LuCaP family of xenografts established from primary neoplasm to metastasis. Expression of four stem cell...
10.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, et al.
Nat Cell Biol
. 2015 Nov;
17(12):1523-35.
PMID: 26571212
For nearly a century developmental biologists have recognized that cells from embryos can differ in their potential to differentiate into distinct cell types. Recently, it has been recognized that embryonic...