Methods : a Companion to Methods in Enzymology
Overview
Methods: A Companion to Methods in Enzymology is a reputable scientific journal that focuses on the latest advancements in experimental techniques and methodologies used in enzymology research. It provides a comprehensive platform for researchers to share innovative approaches, protocols, and tools, facilitating the understanding and application of enzymatic processes in various fields of study.
Details
Details
Abbr.
Methods
Start
1990
End
Continuing
Frequency
Eighteen issues a year, 2019-
p-ISSN
1046-2023
e-ISSN
1095-9130
Country
United States
Language
English
Specialty
Biochemistry
Metrics
Metrics
h-index / Ranks: 1068
171
SJR / Ranks: 2969
1162
CiteScore / Ranks: 2014
8.50
JIF / Ranks: 1690
4.8
Recent Articles
1.
Bartoletti S, Raimondi F, Garofani B, Ren E, Ciarpella F, Capodiferro A, et al.
Methods
. 2025 Mar;
238:27-39.
PMID: 40064209
Temporal lobe epilepsy (TLE) is characterized by seizures that originate in temporal structures and that are pharmacoresistant in ∼ 40 % of patients. In the context of a preclinical study...
2.
Zununi Vahed S, Hejazian S, Bakari W, Landon R, Gueguen V, Meddahi-Pelle A, et al.
Methods
. 2025 Mar;
PMID: 40058715
The potential of the cell lysate, secretome and extracellular vesicles (EVs) of mesenchymal stem cells (MSCs) to modulate the immune response and promote tissue regeneration has positioned them as a...
3.
Cui Y, Cui Y, Yi D, Ding Y, Nakai K, Wei L, et al.
Methods
. 2025 Mar;
PMID: 40057293
In recent years, RNA transcriptome sequencing technology has been continuously evolving, ranging from single-cell transcriptomics to spatial transcriptomics. Although these technologies are all based on RNA sequencing, each sequencing technology...
4.
Yuan S, Zhao C, Liu L, Zhou G
Methods
. 2025 Mar;
PMID: 40049434
Accurate analysis of molecular structures and the rapid generation of valid molecules remain significant challenges in De Novo drug design. In this study, we propose the Multinomial Generated Diffusion Model...
5.
Wang X, Wu K, Liu R, Wang K, Xie W, Zhai X, et al.
Methods
. 2025 Mar;
238:11-18.
PMID: 40049433
Parkinson's disease (PD) is a neurodegenerative disorder caused by excessive reactive halogen species leading to the death of dopaminergic (DA) neurons, which disrupts the coordination of normal physiological structures and...
6.
Zhang L, Xiong S, Xu L, Liang J, Zhao X, Zhang H, et al.
Methods
. 2025 Mar;
238:19-26.
PMID: 40049432
Antimicrobial peptides (AMPs) are promising candidates for addressing the global challenge of antibiotic resistance due to their broad-spectrum antimicrobial properties. Traditional AMP identification methods, while effective, are labor-intensive and time-consuming....
7.
Xu C, Zhu Z, Chen X, Lu M, Wang C, Zhang S, et al.
Methods
. 2025 Mar;
237:34-44.
PMID: 40049431
Epilepsy is a prevalent neurological disorder that affects over 70 million individuals worldwide and is often associated with cognitive impairments. Despite the widespread impact of epilepsy and cognitive impairments, the...
8.
Wegierek-Ciuk A, Baczewska M, Galczynska K, Ortega P, de la Mata F, Kujawinska M, et al.
Methods
. 2025 Mar;
238:1-10.
PMID: 40023352
Resistance of cancer cells to chemotherapy is one of the major causes of treatment failure and poor patient survival. Reduced cellular response to drugs can result from their genetic diversity,...
9.
Michurina S, Goltseva Y, Ratner E, Dergilev K, Shestakova E, Minniakhmetov I, et al.
Methods
. 2025 Mar;
237:9-18.
PMID: 40023351
Lipid droplets (LDs) are dynamic organelles that are present in almost all cell types, with a particularly high prevalence in adipocytes. The phenotype of LDs in these cells reflects their...
10.
Thangariyal S, Bhat S, Mittal A, Debishree Subudhi P, Negi P, Bihari C, et al.
Methods
. 2025 Mar;
237:1-8.
PMID: 40023350
Bacterial vesicles (BVs) are membrane-bound extracellular vesicles (EV) released from bacteria. They are known to play crucial role in bacterial communication, host-pathogen interactions, transfer of virulence factors, contribute to immune...