Jayne S Danska
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Explore the profile of Jayne S Danska including associated specialties, affiliations and a list of published articles.
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49
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2849
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Recent Articles
1.
Granato A, Xie Q, Wong A, Yau C, Noseworthy R, Chen T, et al.
Diabetes
. 2025 Feb;
PMID: 39982433
Obesity in childhood is associated with adulthood obesity, type 2 diabetes (T2D), and future metabolic complications. The gut microbiome is a modifier of host metabolic function with altered bacterial composition...
2.
Renwick S, Furst A, Knip M, Bode L, Danska J, Allen-Vercoe E
Microbiome
. 2025 Feb;
13(1):44.
PMID: 39920790
Background: Synthetic human milk oligosaccharides (HMOs) are used to supplement infant formula despite limited understanding of their impact on the post-weaned developing gut microbiota. Here, we assess the influence of...
3.
Granato A, Renwick S, Yau C, Kong T, Daigneault M, Knip M, et al.
Microbiome
. 2024 Dec;
12(1):255.
PMID: 39639333
Background: The human gut microbiota is inoculated at birth and undergoes a process of assembly and diversification during the first few years of life. Studies in mice and humans have...
4.
Yau C, Danska J
Immunol Rev
. 2024 Aug;
325(1):23-45.
PMID: 39166298
Type 1 diabetes (T1D) results from a complex interplay of genetic predisposition, immunological dysregulation, and environmental triggers, that culminate in the destruction of insulin-secreting pancreatic β cells. This review provides...
5.
Granato A, Ryan P, Wong A, Hamilton J, Danska J
JCEM Case Rep
. 2024 Jun;
2(6):luae091.
PMID: 38832003
Rapid onset obesity with hypoventilation, hypothalamic, and autonomic dysregulation (ROHHAD) syndrome in childhood is characterized by abrupt onset weight gain and dysautonomia with variable neuroendocrine involvement. In the absence of...
6.
Xie Q, Oh S, Wong A, Yau C, Herold K, Danska J
Sci Transl Med
. 2023 Oct;
15(719):eadh0353.
PMID: 37878676
Immune-targeted therapies have efficacy for treatment of autoinflammatory diseases. For example, treatment with the T cell-specific anti-CD3 antibody teplizumab delayed disease onset in participants at high risk for type 1...
7.
Van J, Luo Y, Danska J, Dai F, Alexeeff S, Gunderson E, et al.
Metabolism
. 2023 Oct;
149:155695.
PMID: 37802200
Background: Gestational diabetes (GDM) is a distinctive form of diabetes that first presents in pregnancy. While most women return to normoglycemia after delivery, they are nearly ten times more likely...
8.
Rajakumar S, Grandal I, Minden M, Hitzler J, Guidos C, Danska J
Cell Rep Med
. 2022 Jan;
2(12):100470.
PMID: 35028611
Acute lymphoblastic leukemia (ALL) dissemination to the central nervous system (CNS) is a challenging clinical problem whose underlying mechanisms are poorly understood. Here, we show that primary human ALL samples...
9.
Vanner R, Dobson S, Gan O, McLeod J, Schoof E, Grandal I, et al.
Blood Cancer Discov
. 2022 Jan;
3(1):16-31.
PMID: 35019858
Central nervous system (CNS) dissemination of B-precursor acute lymphoblastic leukemia (B-ALL) has poor prognosis and remains a therapeutic challenge. Here we performed targeted DNA sequencing as well as transcriptional and...
10.
Rajakumar S, Danska J
Mol Cell Oncol
. 2021 Feb;
8(1):1835423.
PMID: 33553597
Skeletal morbidities continue to cause acute and long-term burdens for B-ALL patients underscoring the need to identify the mechanisms underlying these processes and to develop effective therapies. Our recent findings...