Jay W Schneider
Overview
Explore the profile of Jay W Schneider including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
2781
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Kato M, Han T, Xie S, Shi K, Du X, Wu L, et al.
Cell
. 2012 May;
149(4):753-67.
PMID: 22579281
Eukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many proteins within these bodies contain KH or RRM RNA-binding domains as well as low complexity (LC) sequences of...
22.
Russell J, Goetsch S, Aguilar H, Coe H, Luo X, Liu N, et al.
ACS Chem Biol
. 2012 Apr;
7(6):1077-83.
PMID: 22462679
Chemical biology promises discovery of new and unexpected mechanistic pathways, protein functions and disease targets. Here, we probed the mechanism-of-action and protein targets of 3,5-disubstituted isoxazoles (Isx), cardiomyogenic small molecules...
23.
Russell J, Goetsch S, Aguilar H, Frantz D, Schneider J
ACS Chem Biol
. 2012 Mar;
7(6):1067-76.
PMID: 22413910
Targeting native progenitors with small molecule pharmaceuticals that direct cell fate decisions is an attractive approach for regenerative medicine. Here, we show that 3,5-disubstituted isoxazoles (Isx), stem cell-modulator small molecules...
24.
Dioum E, Osborne J, Goetsch S, Russell J, Schneider J, Cobb M
Proc Natl Acad Sci U S A
. 2011 Dec;
108(51):20713-8.
PMID: 22143803
New drugs for preserving and restoring pancreatic β-cell function are critically needed for the worldwide epidemic of type 2 diabetes and the cure for type 1 diabetes. We previously identified...
25.
Zhang L, Li P, Hsu T, Aguilar H, Frantz D, Schneider J, et al.
Differentiation
. 2011 Mar;
81(4):233-42.
PMID: 21419563
In the central nervous system (CNS), neural stem cells (NSCs) differentiate into neurons, astrocytes, and oligodendrocytes--these cell lineages are considered unidirectional and irreversible under normal conditions. The introduction of a...
26.
Russell J, Goetsch S, Gaiano N, Hill J, Olson E, Schneider J
Circ Res
. 2010 Nov;
108(1):51-9.
PMID: 21106942
Rationale: Transgenic Notch reporter mice express enhanced green fluorescent protein in cells with C-promoter binding factor-1 response element transcriptional activity (CBF1-RE(x)₄-EGFP), providing a unique and powerful tool for identifying and...
27.
Simsek T, Kocabas F, Zheng J, DeBerardinis R, Mahmoud A, Olson E, et al.
Cell Stem Cell
. 2010 Sep;
7(3):380-90.
PMID: 20804973
Bone marrow transplantation is the primary therapy for numerous hematopoietic disorders. The efficiency of bone marrow transplantation depends on the function of long-term hematopoietic stem cells (LT-HSCs), which is markedly...
28.
Schneider J, Gao Z, Li S, Farooqi M, Tang T, Bezprozvanny I, et al.
Nat Chem Biol
. 2008 Jun;
4(7):408-10.
PMID: 18552832
We probed an epigenetic regulatory path from small molecule to neuronal gene activation. Isoxazole small molecules triggered robust neuronal differentiation in adult neural stem cells, rapidly signaling to the neuronal...
29.
Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry M, et al.
Proc Natl Acad Sci U S A
. 2008 Apr;
105(16):6063-8.
PMID: 18420817
The clinical success of stem cell therapy for myocardial repair hinges on a better understanding of cardiac fate mechanisms. We have identified small molecules involved in cardiac fate by screening...
30.
Barth A, Kizana E, Smith R, Terrovitis J, Dong P, Leppo M, et al.
Mol Ther
. 2008 Apr;
16(5):957-64.
PMID: 18388932
Cardiosphere-derived resident cardiac stem cells (CDCs) are readily isolated from adult hearts and confer functional benefit in animal models of heart failure. To study cardiogenic differentiation in CDCs, we developed...