Jay W Schneider
Overview
Explore the profile of Jay W Schneider including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
2781
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Matsui T, Nieto-Estevez V, Kyrychenko S, Schneider J, Hsieh J
Development
. 2017 Jan;
144(6):1025-1034.
PMID: 28087635
The tumor suppressor retinoblastoma protein (RB) regulates S-phase cell cycle entry via E2F transcription factors. Knockout (KO) mice have shown that RB plays roles in cell migration, differentiation and apoptosis,...
12.
Morales C, Li D, Pedrozo Z, May H, Jiang N, Kyrychenko V, et al.
Sci Signal
. 2016 Apr;
9(422):ra34.
PMID: 27048565
Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of these transcriptional responses by pharmacological inhibition of class I histone...
13.
Li D, Wang Z, Ding G, Tan W, Luo X, Criollo A, et al.
Circulation
. 2016 Mar;
133(17):1668-87.
PMID: 26984939
Background: The clinical use of doxorubicin is limited by cardiotoxicity. Histopathological changes include interstitial myocardial fibrosis and the appearance of vacuolated cardiomyocytes. Whereas dysregulation of autophagy in the myocardium has...
14.
Kalwat M, Huang Z, Wichaidit C, McGlynn K, Earnest S, Savoia C, et al.
ACS Chem Biol
. 2016 Feb;
11(4):1128-36.
PMID: 26828310
Novel strategies are needed to modulate β-cell differentiation and function as potential β-cell replacement or restorative therapies for diabetes. We previously demonstrated that small molecules based on the isoxazole scaffold...
15.
Burchfield J, Paul A, Lanka V, Tan W, Kong Y, McCallister C, et al.
J Investig Med
. 2016 Jan;
64(1):50-62.
PMID: 26755814
Adipose-derived stem cells (ADSCs) have myocardial regeneration potential, and transplantation of these cells following myocardial infarction (MI) in animal models leads to modest improvements in cardiac function. We hypothesized that...
16.
Shen J, Meng X, Wight-Carter M, Day T, Goetsch S, Forni S, et al.
Hum Mol Genet
. 2015 Feb;
24(11):3181-91.
PMID: 25701874
Fabry disease is caused by deficient activity of lysosomal enzyme α-galactosidase A. The enzyme deficiency results in intracellular accumulation of glycosphingolipids, leading to a variety of clinical manifestations including hypertrophic...
17.
Singh S, Canseco D, Manda S, Shelton J, Chirumamilla R, Goetsch S, et al.
Proc Natl Acad Sci U S A
. 2013 Dec;
111(1):E129-38.
PMID: 24367119
Mammalian skeletal muscle can remodel, repair, and regenerate itself by mobilizing satellite cells, a resident population of myogenic progenitor cells. Muscle injury and subsequent activation of myogenic progenitor cells is...
18.
Velasquez L, Sutherland L, Liu Z, Grinnell F, Kamm K, Schneider J, et al.
Proc Natl Acad Sci U S A
. 2013 Oct;
110(42):16850-5.
PMID: 24082095
Myocardin-related transcription factors (MRTFs) regulate cellular contractility and motility by associating with serum response factor (SRF) and activating genes involved in cytoskeletal dynamics. We reported previously that MRTF-A contributes to...
19.
20.
Schneider J, Goetsch S, Leng X, Ludwig S, Russell J, Yang C, et al.
ACS Chem Neurosci
. 2012 Aug;
3(7):557-68.
PMID: 22860225
Acidosis, a critical aspect of central nervous system (CNS) pathophysiology and a metabolic corollary of the hypoxic stem cell niche, could be an expedient trigger for hippocampal neurogenesis and brain...