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Jenny Hsieh

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Citations 4072
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Recent Articles
1.
Meyer-Acosta K, Diaz-Guerra E, Varma P, Aruk A, Mirsadeghi S, Perez A, et al.
bioRxiv . 2024 Oct; PMID: 39416105
Apolipoprotein E4 ( ) is the leading genetic risk factor for Alzheimer's disease. While most studies examine the role of in aging, imaging, and cognitive assessments reveal that influences brain...
2.
Adeyeye A, Mirsadeghi S, Gutierrez M, Hsieh J
Epilepsy Behav . 2024 Aug; 159:109982. PMID: 39181108
Epilepsy is a chronic neurological disorder characterized by recurring, unprovoked seizures, asymmetrical electroencephalogram patterns, and other pathological abnormalities. The hippocampus plays a pivotal role in learning, memory consolidation, attentional control,...
3.
McMahon C, Hurley E, Perez A, Estrada M, Lodge D, Hsieh J
JCI Insight . 2024 May; 9(13). PMID: 38781563
Prenatal exposure to viral pathogens has been known to cause the development of neuropsychiatric disorders in adulthood. Furthermore, COVID-19 has been associated with a variety of neurological manifestations, raising the...
4.
Moynihan D, Monaco S, Ting T, Narasimhalu K, Hsieh J, Kam S, et al.
Sci Rep . 2024 May; 14(1):10084. PMID: 38698204
No abstract available.
5.
Abelman R, Fitzpatrick J, Byanova K, Zawedde J, Sanyu I, Byanyima P, et al.
Open Forum Infect Dis . 2024 Mar; 11(3):ofae033. PMID: 38456193
Background: Preserved ratio impaired spirometry (PRISm), defined as a normal ratio of forced expiratory volume in 1 second (FEV) to forced vital capacity (≥0.70) with low FEV (<80% predicted), has...
6.
Moynihan D, Monaco S, Ting T, Narasimhalu K, Hsieh J, Kam S, et al.
Sci Rep . 2024 Feb; 14(1):5056. PMID: 38424111
Rare genetic diseases affect 5-8% of the population but are often undiagnosed or misdiagnosed. Electronic health records (EHR) contain large amounts of data, which provide opportunities for analysing and mining....
7.
Nieto-Estevez V, Varma P, Mirsadeghi S, Caballero J, Gamero-Alameda S, Hosseini A, et al.
bioRxiv . 2024 Feb; PMID: 38328230
Infantile spasms, with an incidence of 1.6 to 4.5 per 10,000 live births, are a relentless and devastating childhood epilepsy marked by severe seizures but also leads to lifelong intellectual...
8.
Choi I, Cha J, Kim S, Hsieh J, Cho K
JCI Insight . 2024 Jan; 9(1). PMID: 38193536
Prolonged seizures can disrupt stem cell behavior in the adult hippocampus, an important brain structure for spatial memory. Here, using a mouse model of pilocarpine-induced status epilepticus (SE), we characterized...
9.
Byanova K, Fitzpatrick J, Jan A, McGing M, Hartman-Filson M, Farr C, et al.
PLoS One . 2023 Jul; 18(7):e0288803. PMID: 37463173
Objectives: An isolated reduction in the diffusing capacity for carbon monoxide (DLco; iso↓DLco) is one of the most common pulmonary function test (PFT) abnormalities in people living with HIV (PWH),...
10.
Hurley E, Mozolewski P, Dobrowolski R, Hsieh J
Stem Cell Reports . 2023 Jun; 18(7):1516-1533. PMID: 37352850
Alzheimer's disease (AD) is the most common neurodegenerative disorder, but its root cause may lie in neurodevelopment. PSEN1 mutations cause the majority of familial AD, potentially by disrupting proper Notch...