Jasmien Hoebeeck
Overview
Explore the profile of Jasmien Hoebeeck including associated specialties, affiliations and a list of published articles.
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15
Citations
413
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Recent Articles
1.
Decock A, Ongenaert M, Hoebeeck J, De Preter K, Van Peer G, Van Criekinge W, et al.
Genome Biol
. 2012 Oct;
13(10):R95.
PMID: 23034519
Background: Accurate outcome prediction in neuroblastoma, which is necessary to enable the optimal choice of risk-related therapy, remains a challenge. To improve neuroblastoma patient stratification, this study aimed to identify...
2.
De Brouwer S, De Preter K, Kumps C, Zabrocki P, Porcu M, Westerhout E, et al.
Clin Cancer Res
. 2010 Aug;
16(17):4353-62.
PMID: 20719933
Purpose: Activating mutations of the anaplastic lymphoma kinase (ALK) were recently described in neuroblastoma. We carried out a meta-analysis of 709 neuroblastoma tumors to determine their frequency and mutation spectrum...
3.
Lefever S, Hoebeeck J, Pattyn F, Tusnady G, De Paepe A, Speleman F, et al.
Epigenetics
. 2010 Feb;
5(2):159-63.
PMID: 20160504
Abnormalities in DNA methylation of CpG islands that play a role in gene regulation affect gene expression and hence play a role in disease, including cancer. Bisulfite-based DNA methylation analysis...
4.
Van Roy N, De Preter K, Hoebeeck J, Van Maerken T, Pattyn F, Mestdagh P, et al.
Genome Med
. 2009 Jul;
1(7):74.
PMID: 19638189
Neuroblastoma is one of the most common solid tumors of childhood, arising from immature sympathetic nervous system cells. The clinical course of patients with neuroblastoma is highly variable, ranging from...
5.
Hoebeeck J, De Wilde B, Michels E, Combaret V, Yigit N, Smet E, et al.
Cancer Invest
. 2009 Jun;
27(8):857-68.
PMID: 19544108
Pinpointing critical regions of recurrent loss may help localize tumor suppressor genes. To determine the regions of loss on chromosome 3p in neuroblastoma, we performed loss of heterozygosity analysis using...
6.
Hoebeeck J, Michels E, Pattyn F, Combaret V, Vermeulen J, Yigit N, et al.
Cancer Lett
. 2008 Sep;
273(2):336-46.
PMID: 18819746
CpG island hypermethylation has been recognized as an alternative mechanism for tumor suppressor gene inactivation. In this study, we performed methylation-specific PCR (MSP) to investigate the methylation status of 10...
7.
Michels E, Hoebeeck J, De Preter K, Schramm A, Brichard B, De Paepe A, et al.
BMC Cancer
. 2008 Jun;
8:173.
PMID: 18559103
Background: Recurrent loss of part of the long arm of chromosome 11 is a well established hallmark of a subtype of aggressive neuroblastomas. Despite intensive mapping efforts to localize the...
8.
Michels E, Vandesompele J, De Preter K, Hoebeeck J, Vermeulen J, Schramm A, et al.
Genes Chromosomes Cancer
. 2007 Sep;
46(12):1098-108.
PMID: 17823929
High-resolution array comparative genomic hybridization (arrayCGH) profiling was performed on 75 primary tumors and 29 cell lines to gain further insight into the genetic heterogeneity of neuroblastoma and to refine...
9.
Hoebeeck J, Speleman F, Vandesompele J
Methods Mol Biol
. 2007 Mar;
353:205-26.
PMID: 17332643
Changes in copy number of genes contribute to the pathogenesis of various genetic disorders and cancer. The status of a gene has not only diagnostic value but sometimes directs treatment...
10.
Hoebeeck J, Michels E, Menten B, Van Roy N, Eggert A, Schramm A, et al.
Int J Cancer
. 2006 Nov;
120(3):533-8.
PMID: 17096344
The recurrent loss of 3p segments in neuroblastoma suggests the implication of 1 or more tumor suppressor genes but thus far few efforts have been made to pinpoint their detailed...