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Jacob I Sznajder

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Articles 158
Citations 5363
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Recent Articles
1.
Runyan C, Luo L, Welch L, Lu Z, Chen F, Schleck M, et al.
bioRxiv . 2025 Jan; PMID: 39868236
Sarcopenia, which diminishes lifespan and healthspan in the elderly, is commonly exacerbated by viral pneumonia, including influenza and COVID-19. In a study of influenza A pneumonia in mice, young mice...
2.
Do-Umehara H, Chen C, Urich D, Zhou L, Qiu J, Jang S, et al.
Nat Immunol . 2025 Jan; 26(2):324. PMID: 39774410
No abstract available.
3.
Bailey J, Puritz C, Senkow K, Markov N, Diaz E, Jonasson E, et al.
Nat Immunol . 2025 Jan; 26(2):323. PMID: 39774409
No abstract available.
4.
Bailey J, Puritz C, Senkow K, Markov N, Diaz E, Jonasson E, et al.
Nat Immunol . 2024 Oct; 25(11):2097-2109. PMID: 39367123
Monocyte-derived alveolar macrophages drive lung injury and fibrosis in murine models and are associated with pulmonary fibrosis in humans. Monocyte-derived alveolar macrophages have been suggested to develop a phenotype that...
5.
Kouri F, Hurley L, Daniel W, Day E, Hua Y, Hao L, et al.
Genes Dev . 2024 May; 38(7-8):355. PMID: 38772726
No abstract available.
6.
Phelan D, Reddan B, Shigemura M, Sznajder J, Crean D, Cummins E
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38474099
Hypercapnia occurs when the partial pressure of carbon dioxide (CO) in the blood exceeds 45 mmHg. Hypercapnia is associated with several lung pathologies and is transcriptionally linked to suppression of...
7.
Bailey J, Lavelle B, Miller J, Jimenez M, Lim P, Orban Z, et al.
Am J Med . 2023 May; 138(1):108-120. PMID: 37220832
Background: Persistent multi-organ symptoms after coronavirus disease 2019 (COVID-19) have been termed "long COVID" or "post-acute sequelae of SARS-CoV-2 infection." The complexity of these clinical manifestations posed challenges early in...
8.
Stoeger T, Grant R, McQuattie-Pimentel A, Anekalla K, Liu S, Tejedor-Navarro H, et al.
Nat Aging . 2023 Apr; 2(12):1191-1206. PMID: 37118543
Aging is among the most important risk factors for morbidity and mortality. To contribute toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data from multiple studies. Here, we...
9.
Phelan D, Mota C, Strowitzki M, Shigemura M, Sznajder J, Crowe L, et al.
Immunol Cell Biol . 2023 Mar; 101(6):556-577. PMID: 36967673
CO is produced during aerobic respiration. Normally, levels of CO in the blood are tightly regulated but pCO can rise (hypercapnia, pCO  > 45 mmHg) in patients with lung diseases,...
10.
Dada L, Welch L, Magnani N, Ren Z, Han H, Brazee P, et al.
JCI Insight . 2023 Jan; 8(4). PMID: 36626234
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory...