Lynn C Welch
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Explore the profile of Lynn C Welch including associated specialties, affiliations and a list of published articles.
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28
Citations
773
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Recent Articles
1.
Runyan C, Luo L, Welch L, Lu Z, Chen F, Schleck M, et al.
bioRxiv
. 2025 Jan;
PMID: 39868236
Sarcopenia, which diminishes lifespan and healthspan in the elderly, is commonly exacerbated by viral pneumonia, including influenza and COVID-19. In a study of influenza A pneumonia in mice, young mice...
2.
Dada L, Welch L, Magnani N, Ren Z, Han H, Brazee P, et al.
JCI Insight
. 2023 Jan;
8(4).
PMID: 36626234
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory...
3.
Weng A, Herrerias M, Watanabe S, Welch L, Flozak A, Grant R, et al.
Am J Respir Cell Mol Biol
. 2022 Feb;
66(5):564-576.
PMID: 35202558
Epithelial polyploidization after injury is a conserved phenomenon recently shown to improve barrier restoration during wound healing. Whether lung injury can induce alveolar epithelial polyploidy is not known. We show...
4.
Ceco E, Celli D, Weinberg S, Shigemura M, Welch L, Volpe L, et al.
Front Physiol
. 2021 Feb;
11:630910.
PMID: 33551852
Muscle dysfunction often occurs in patients with chronic obstructive pulmonary diseases (COPD) and affects ventilatory and non-ventilatory skeletal muscles. We have previously reported that hypercapnia (elevated CO levels) causes muscle...
5.
Shigemura M, Welch L, Sznajder J
Front Physiol
. 2020 Dec;
11:598122.
PMID: 33329047
Carbon dioxide (CO) is produced in eukaryotic cells primarily during aerobic respiration, resulting in higher CO levels in mammalian tissues than those in the atmosphere. CO like other gaseous molecules...
6.
Runyan C, Welch L, Lecuona E, Shigemura M, Amarelle L, Abdala-Valencia H, et al.
Aging Cell
. 2020 Jul;
19(9):e13180.
PMID: 32720752
Skeletal muscle dysfunction in survivors of pneumonia disproportionately affects older individuals in whom it causes substantial morbidity. We found that skeletal muscle recovery was impaired in old compared with young...
7.
Bharat A, Angulo M, Sun H, Akbarpour M, Alberro A, Cheng Y, et al.
Am J Respir Cell Mol Biol
. 2020 Apr;
63(2):244-254.
PMID: 32275835
Delayed lung repair leads to alveolopleural fistulae, which are a major cause of morbidity after lung resections. We have reported that intrapleural hypercapnia is associated with delayed lung repair after...
8.
Shigemura M, Lecuona E, Angulo M, Dada L, Edwards M, Welch L, et al.
Sci Rep
. 2019 Dec;
9(1):18251.
PMID: 31796806
Carbon dioxide (CO) is sensed by cells and can trigger signals to modify gene expression in different tissues leading to changes in organismal functions. Despite accumulating evidence that several pathways...
9.
Amarelle L, Katzen J, Shigemura M, Welch L, Cajigas H, Peteranderl C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2019 Mar;
316(6):L1094-L1106.
PMID: 30892074
Cardiac glycosides (CGs) are used primarily for cardiac failure and have been reported to have other effects, including inhibition of viral replication. Here we set out to study mechanisms by...
10.
Radigan K, Nicholson T, Welch L, Chi M, Amarelle L, Angulo M, et al.
J Immunol
. 2018 Dec;
202(2):484-493.
PMID: 30530483
Muscle dysfunction is common in patients with adult respiratory distress syndrome and is associated with morbidity that can persist for years after discharge. In a mouse model of severe influenza...