Alexander V Misharin
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Explore the profile of Alexander V Misharin including associated specialties, affiliations and a list of published articles.
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92
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5704
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Recent Articles
1.
Runyan C, Luo L, Welch L, Lu Z, Chen F, Schleck M, et al.
bioRxiv
. 2025 Jan;
PMID: 39868236
Sarcopenia, which diminishes lifespan and healthspan in the elderly, is commonly exacerbated by viral pneumonia, including influenza and COVID-19. In a study of influenza A pneumonia in mice, young mice...
2.
Guggilla V, Kang M, Bak M, Tran S, Pawlowski A, Nannapaneni P, et al.
medRxiv
. 2025 Jan;
PMID: 39867358
Identifying immunosuppressed patients using structured data can be challenging. Large language models effectively extract structured concepts from unstructured clinical text. Here we show that GPT-4o outperforms traditional approaches in identifying...
3.
Bailey J, Puritz C, Senkow K, Markov N, Diaz E, Jonasson E, et al.
Nat Immunol
. 2025 Jan;
26(2):323.
PMID: 39774409
No abstract available.
4.
Bailey J, Puritz C, Senkow K, Markov N, Diaz E, Jonasson E, et al.
Nat Immunol
. 2024 Oct;
25(11):2097-2109.
PMID: 39367123
Monocyte-derived alveolar macrophages drive lung injury and fibrosis in murine models and are associated with pulmonary fibrosis in humans. Monocyte-derived alveolar macrophages have been suggested to develop a phenotype that...
5.
Markov N, Ren Z, Senkow K, Grant R, Gao C, Malsin E, et al.
Nat Immunol
. 2024 Aug;
25(9):1607-1622.
PMID: 39138384
The evolution of T cell molecular signatures in the distal lung of patients with severe pneumonia is understudied. Here, we analyzed T cell subsets in longitudinal bronchoalveolar lavage fluid samples...
6.
Hynds R, Magin C, Ikonomou L, Aschner Y, Beers M, Burgess J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 May;
327(3):L327-L340.
PMID: 38772903
Repair and regeneration of a diseased lung using stem cells or bioengineered tissues is an exciting therapeutic approach for a variety of lung diseases and critical illnesses. Over the past...
7.
Waypa G, Smith K, Mungai P, Dudley V, Helmin K, Singer B, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38722697
Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back...
8.
Grant R, Poor T, Sichizya L, Diaz E, Bailey J, Soni S, et al.
JCI Insight
. 2024 Mar;
9(8).
PMID: 38502186
BACKGROUNDSurvivors of pneumonia, including SARS-CoV-2 pneumonia, are at increased risk for cognitive dysfunction and dementia. In rodent models, cognitive dysfunction following pneumonia has been linked to the systemic release of...
9.
Guttenberg M, Vose A, Birukova A, Lewars K, Cumming R, Albright M, et al.
Am J Respir Cell Mol Biol
. 2024 Feb;
70(6):493-506.
PMID: 38386777
Lung inflammation, caused by acute exposure to ozone (O), one of the six criteria air pollutants, is a significant source of morbidity in susceptible individuals. Alveolar macrophages (AMØs) are the...
10.
Markov N, Ren Z, Senkow K, Grant R, Gao C, Malsin E, et al.
bioRxiv
. 2024 Jan;
PMID: 38168346
Pathogen clearance and resolution of inflammation in patients with pneumonia require an effective local T cell response. Nevertheless, local T cell activation may drive lung injury, particularly during prolonged episodes...