Genes & Development
Overview
Genes & Development is a prestigious scientific journal that focuses on the latest research in the field of molecular and cellular biology. It publishes groundbreaking studies on gene regulation, development, and evolution, providing a comprehensive understanding of how genes control various biological processes. With its rigorous peer-review process and interdisciplinary approach, Genes & Development serves as a vital resource for scientists and researchers seeking to unravel the complexities of gene expression and its impact on development and disease.
Details
Details
Abbr.
Genes Dev
Start
1987
End
Continuing
Frequency
Semimonthly
p-ISSN
0890-9369
e-ISSN
1549-5477
Country
United States
Language
English
Specialty
Molecular Biology
Metrics
Metrics
h-index / Ranks: 38
479
SJR / Ranks: 259
5015
CiteScore / Ranks: 375
19.50
JIF / Ranks: 426
10.5
Recent Articles
1.
Massoni S, Evans N, Hantke I, Fenton C, Torpey J, Collins K, et al.
Genes Dev
. 2025 Mar;
PMID: 40086879
Bacterial protein degradation machinery consists of chaperone-protease complexes that play vital roles in bacterial growth and development and have sparked interest as novel antimicrobial targets. ClpC-ClpP (ClpCP) is one such...
2.
Larue L
Genes Dev
. 2025 Mar;
PMID: 40086878
Metastasis and therapy resistance drive cancer-related deaths, with melanoma cells exhibiting phenotypic plasticity that allows them to switch between proliferative and invasive states. In this issue of , Chocarro-Calvo and...
3.
Setlow P
Genes Dev
. 2025 Mar;
PMID: 40086877
Developing spores (forespores) of lack TCA cycle and amino acid and ribonucleotide biosynthetic enzymes but still carry out much macromolecular synthesis to make a spore-but how and why? Work by...
4.
Riley E, Lyda J, Reyes-Matte O, Sugie J, Kasu I, Enustun E, et al.
Genes Dev
. 2025 Mar;
PMID: 40086876
sporulation entails a dramatic transformation of the two cells required to assemble a dormant spore, with the larger mother cell engulfing the smaller forespore to produce the "cell within a...
5.
Chocarro-Calvo A, Jociles-Ortega M, Garcia-Martinez J, Louphrasitthiphol P, Carvalho-Marques S, Vivas-Garcia Y, et al.
Genes Dev
. 2025 Feb;
PMID: 40015991
Interaction between the tumor microenvironment and cancer cell plasticity drives intratumor phenotypic heterogeneity and underpins disease progression and nongenetic therapy resistance. Phenotype-specific expression of the AXL receptor tyrosine kinase is...
6.
Hermant C, Mourra-Diaz C, Oomen M, Altamirano-Pacheco L, Pal M, Nakatani T, et al.
Genes Dev
. 2025 Feb;
PMID: 40015990
The regulatory circuitry of cell-specific transcriptional programs is thought to be influenced by transposable elements (TEs), whereby TEs serve as raw material for the diversification and genome-wide distribution of genetic...
7.
Martin A, Schabort J, Bartke-Croughan R, Tran S, Preetham A, Lu R, et al.
Genes Dev
. 2025 Feb;
PMID: 40015989
Mutations in the shelterin protein POT1 are associated with diverse cancers and thought to drive carcinogenesis by impairing POT1's suppression of aberrant telomere elongation. To classify clinical variants of uncertain...
8.
Jeong J, Hertel K, Shi Y
Genes Dev
. 2025 Feb;
39(5-6):301-303.
PMID: 39939174
Alternative splicing (AS) is regulated by a myriad of RNA-binding proteins (RBPs) in a coordinated manner. However, most studies characterize RBPs individually. In this issue of , Peyda and colleagues...
9.
Wolf van der Meer J, Larue A, van der Knaap J, Chalkley G, Sijm A, Beikmohammadi L, et al.
Genes Dev
. 2025 Feb;
39(5-6):401-422.
PMID: 39919828
Pathogenic variants in the ubiquitin-specific protease 7 () gene cause a neurodevelopmental disorder called Hao-Fountain syndrome. However, it remains unclear which of USP7's pleiotropic functions are relevant for neurodevelopment. Here,...
10.
Hyrien O, Guilbaud G, Krude T
Genes Dev
. 2025 Feb;
39(5-6):304-324.
PMID: 39904559
Mammalian DNA replication origins have been historically difficult to identify and their determinants are still unresolved. Here, we first review methods developed over the last decades to map replication initiation...