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Hardev Pandha

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Articles 148
Citations 4130
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Recent Articles
11.
Relph K, Arif M, Pandha H, Annels N, Simpson G
Methods Mol Biol . 2023 Jul; 2684:319-327. PMID: 37410244
Oncolytic viruses are biological agents which can easily be delivered at high doses directly to the bladder through a catheter (intravesical), with low risk of systemic uptake and toxicity. To...
12.
Darst B, Shen J, Madduri R, Rodriguez A, Xiao Y, Sheng X, et al.
Am J Hum Genet . 2023 Jun; 110(7):1200-1206. PMID: 37311464
Genome-wide polygenic risk scores (GW-PRSs) have been reported to have better predictive ability than PRSs based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several...
13.
Darst B, Shen J, Madduri R, Rodriguez A, Xiao Y, Sheng X, et al.
medRxiv . 2023 Jun; PMID: 37292833
Genome-wide polygenic risk scores (GW-PRS) have been reported to have better predictive ability than PRS based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several...
14.
Miller K, Henry I, Maylin Z, Smith C, Arunachalam E, Pandha H, et al.
Front Oncol . 2023 Mar; 13:1129140. PMID: 36937454
Persistent androgen receptor (AR) signalling is the main driver of prostate cancer (PCa). Truncated isoforms of the AR called androgen receptor variants (AR-Vs) lacking the ligand binding domain often emerge...
15.
Muazzam A, Spick M, Cexus O, Geary B, Azhar F, Pandha H, et al.
Cancers (Basel) . 2023 Feb; 15(4). PMID: 36831393
Prostate cancer is the most common malignant tumour in men. Improved testing for diagnosis, risk prediction, and response to treatment would improve care. Here, we identified a proteomic signature of...
16.
Munjoma N, Isaac G, Muazzam A, Cexus O, Azhar F, Pandha H, et al.
J Proteome Res . 2022 Oct; 21(11):2596-2608. PMID: 36264332
Lipids play a key role in many biological processes, and their accurate measurement is critical to unraveling the biology of diseases and human health. A high throughput HILIC-based (LC-MS) method...
17.
McNally C, Watt J, Kurth M, Lamont J, Moore T, Fitzgerald P, et al.
Front Oncol . 2022 Jun; 12:837127. PMID: 35664747
Background: Almost 50,000 men in the United Kingdom (UK) are diagnosed each year with prostate cancer (PCa). Secondary referrals for investigations rely on serum prostate-specific antigen (PSA) levels and digital...
18.
Samson A, West E, Carmichael J, Scott K, Turnbull S, Kuszlewicz B, et al.
Cancer Immunol Res . 2022 Apr; 10(6):745-756. PMID: 35439304
Improving the chances of curing patients with cancer who have had surgery to remove metastatic sites of disease is a priority area for cancer research. Pexa-Vec (Pexastimogene Devacirepvec; JX-594, TG6006)...
19.
Arunachalam E, Rogers W, Simpson G, Moller-Levet C, Bolton G, Ismael M, et al.
BMC Cancer . 2022 Apr; 22(1):400. PMID: 35418059
Background: Glioblastoma multiforme (GBM) is the most common high-grade malignant brain tumour in adults and arises from the glial cells in the brain. The prognosis of treated GBM remains very...
20.
Evgin L, Kottke T, Tonne J, Thompson J, Huff A, van Vloten J, et al.
Sci Transl Med . 2022 Apr; 14(640):eabn2231. PMID: 35417192
Oncolytic viruses (OVs) encoding a variety of transgenes have been evaluated as therapeutic tools to increase the efficacy of chimeric antigen receptor (CAR)-modified T cells in the solid tumor microenvironment...