Manuel R Teixeira
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Explore the profile of Manuel R Teixeira including associated specialties, affiliations and a list of published articles.
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289
Citations
8507
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Recent Articles
1.
Morais M, Dias F, Figueiredo P, Tavares I, Escudeiro C, Teixeira M, et al.
Int J Nanomedicine
. 2024 Sep;
19:9091-9107.
PMID: 39258003
Purpose: Castration Resistant Prostate Cancer (CRPC) is characterized by poor prognosis and limited therapeutic options. AgNPs functionalized with glucose (G-AgNPs) were observed cytotoxic to CRPC cell lines (PC-3 and Du-145)...
2.
Pires C, Marques I, Saramago A, Moura M, Pojo M, Cabrera R, et al.
Int J Cancer
. 2024 Sep;
156(1):130-144.
PMID: 39251783
The genetic basis of nonsyndromic familial nonmedullary thyroid carcinoma (FNMTC) is still poorly understood, as the susceptibility genes identified so far only account for a small percentage of the genetic...
3.
Lin H, Mazumder H, Sarkar I, Huang P, Eeles R, Kote-Jarai Z, et al.
Sci Rep
. 2024 Aug;
14(1):18677.
PMID: 39134575
Single nucleotide polymorphism (SNP) interactions are the key to improving polygenic risk scores. Previous studies reported several significant SNP-SNP interaction pairs that shared a common SNP to form a cluster,...
4.
Barros A, Mansinho H, Couto N, Teixeira M, Tonin F, Francisco R, et al.
GE Port J Gastroenterol
. 2024 Aug;
31(4):262-272.
PMID: 39114325
Introduction: We aimed to characterize the initial healthcare journey of metastatic pancreatic ductal adenocarcinoma (mPDAC) patients in Portugal, including healthcare provision and factors affecting therapeutic decisions, namely BRCA mutations testing....
5.
Silva M, Ferreira L, Bras N, Torres L, Brandao A, Pinheiro M, et al.
J Biomed Sci
. 2024 Jul;
31(1):74.
PMID: 39014450
Background: Prostate cancer (PrCa) is the most frequently diagnosed cancer in men. Variants in known moderate- to high-penetrance genes explain less than 5% of the cases arising at early-onset (< ...
6.
Peixoto A, Cirnes L, Carvalho A, Andrade M, Brito M, Borralho P, et al.
Front Mol Biosci
. 2024 May;
11:1298522.
PMID: 38721275
[This corrects the article DOI: 10.3389/fmolb.2023.1082915.].
7.
Barnes D, Tyrer J, Dennis J, Leslie G, Bolla M, Lush M, et al.
medRxiv
. 2024 Mar;
PMID: 38496424
Background: Nineteen genomic regions have been associated with high-grade serous ovarian cancer (HGSOC). We used data from the Ovarian Cancer Association Consortium (OCAC), Consortium of Investigators of Modifiers of (CIMBA),...
8.
Wang A, Shen J, Rodriguez A, Saunders E, Chen F, Janivara R, et al.
Nat Genet
. 2023 Nov;
55(12):2065-2074.
PMID: 37945903
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry...
9.
Pinto E, Fridman C, Figueiredo B, Salvador H, Teixeira M, Pinto C, et al.
HGG Adv
. 2023 Oct;
5(1):100244.
PMID: 37794678
The germline TP53 p.R337H mutation is reported as the most common germline TP53 variant. It exists at a remarkably high frequency in the population of southeast Brazil as founder mutation...
10.
Linhares M, Pinto C, Libanio D, Teixeira M, Dinis-Ribeiro M, Brandao C
GE Port J Gastroenterol
. 2023 Sep;
30(4):253-266.
PMID: 37767311
Gastric adenocarcinoma is one of the most frequent and deadly cancers worldwide. However, its incidence is variable, being higher in eastern countries where screening the general population is recommended. On...