H van Steeg
Overview
Explore the profile of H van Steeg including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
1440
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Recent Articles
1.
Rietman M, van der A D, van Oostrom S, Picavet H, Dolle M, van Steeg H, et al.
J Nutr Health Aging
. 2018 Jan;
22(1):8-15.
PMID: 29300416
Objectives: Previous studies showed a U-shaped association between BMI and (physical) frailty. We studied the association between BMI and physical, cognitive, psychological, and social frailty. Furthermore, the overlap between and...
2.
Jongbloed F, Saat T, Verweij M, Payan-Gomez C, Hoeijmakers J, van den Engel S, et al.
Sci Rep
. 2017 Jan;
7:40901.
PMID: 28102354
During kidney transplantation, ischemia-reperfusion injury (IRI) induces oxidative stress. Short-term preoperative 30% dietary restriction (DR) and 3-day fasting protect against renal IRI. We investigated the contribution of macronutrients to this...
3.
Vermeij W, Dolle M, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri C, et al.
Nature
. 2016 Aug;
537(7620):427-431.
PMID: 27556946
Mice deficient in the DNA excision-repair gene Ercc1 (Ercc1) show numerous accelerated ageing features that limit their lifespan to 4-6 months. They also exhibit a 'survival response', which suppresses growth...
4.
Smeekens S, van Steeg H, Bauerle C, Bettenbroek H, Keegstra K, Weisbeek P
Plant Mol Biol
. 2013 Nov;
9(4):377-88.
PMID: 24277090
Many chloroplast proteins are synthesized in the cytoplasm as precursors which contain an amino terminal transit peptide. These precursors are subsequently imported into chloroplast and targeted to one of several...
5.
van Kesteren P, Zwart P, Schaap M, Pronk T, van Herwijnen M, Kleinjans J, et al.
Arch Toxicol
. 2012 Oct;
87(3):505-15.
PMID: 23052197
The traditional 2-year cancer bioassay needs replacement by more cost-effective and predictive tests. The use of toxicogenomics in an in vitro system may provide a more high-throughput method to investigate...
6.
Melis J, Hoogervorst E, van Oostrom C, Zwart E, Breit T, Pennings J, et al.
Oncogene
. 2010 Dec;
30(15):1764-72.
PMID: 21151170
The p53 gene is frequently mutated in cancers and it is vital for cell cycle control, homeostasis and carcinogenesis. We describe a novel p53 mutational spectrum, different to those generally...
7.
Cassee F, de Burbure C, Rambali B, Vleeming W, van de Kuil A, van Steeg H, et al.
Food Chem Toxicol
. 2007 Oct;
46(2):527-36.
PMID: 17936466
We investigated whether inhaling peak concentrations of aldehydes several times daily is more damaging than semi-continuously inhaling low-dose aldehydes. We exposed Xpa-/-p53+/- knock-out mice either intermittently or semi-continuously to mixed...
8.
Maier J, van Steeg H, van Oostrom C, Paschke R, Weiss R, Krohn K
Biochim Biophys Acta
. 2007 May;
1773(6):990-9.
PMID: 17467074
Because thyroid nodules are frequent in areas with iodine deficiency the aim of this study was to characterise molecular events during iodine deficiency that could explain mutagenesis and nodule formation....
9.
Maier J, van Steeg H, van Oostrom C, Karger S, Paschke R, Krohn K
Endocrinology
. 2006 Apr;
147(7):3391-7.
PMID: 16627585
Thyroid tumors are a frequent finding not only in iodine-deficient regions. They are predominantly characterized by somatic genetic changes (e.g. point mutations or rearrangements). Because slow thyroid proliferation is a...
10.
Storer R, French J, Donehower L, Gulezian D, Mitsumori K, Recio L, et al.
Mutat Res
. 2003 Oct;
540(2):165-76.
PMID: 14550500
Genetically altered mouse models (GAMM) for human cancers have been critical to the investigation and characterization of oncogene and tumor suppressor gene expression and function and the associated cancer phenotype....