Gael Cristofari
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Explore the profile of Gael Cristofari including associated specialties, affiliations and a list of published articles.
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48
Citations
1955
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Recent Articles
1.
Matsuo M, Cristofari G
Genes Dev
. 2025 Jan;
39(3-4):183-185.
PMID: 39794124
Long interspersed element-1 (LINE-1) retrotransposons are abundant transposable elements in mammals and significantly influence chromosome structure, chromatin organization, and 3D genome architecture. In this issue of , Ataei et al....
2.
Lesage P, Brasset E, Cristofari G, Gilbert C, Mazel D, Rebollo R, et al.
Mob DNA
. 2024 Oct;
15(1):25.
PMID: 39462418
From April 20 to 23, 2024, three hundred ten researchers from around the world gathered in Saint-Malo, France, at the fourth International Congress on Transposable Elements (ICTE 2024), to present...
3.
Laisne M, Rodgers B, Benlamara S, Wicinski J, Nicolas A, Djerroudi L, et al.
Oncogene
. 2024 Mar;
43(18):1369-1385.
PMID: 38467851
Breast cancer is the most prevalent type of cancer in women worldwide. Within breast tumors, the basal-like subtype has the worst prognosis, prompting the need for new tools to understand,...
4.
Lanciano S, Philippe C, Sarkar A, Pratella D, Domrane C, Doucet A, et al.
Cell Genom
. 2024 Feb;
4(2):100498.
PMID: 38309261
Long interspersed element 1 (L1) retrotransposons are implicated in human disease and evolution. Their global activity is repressed by DNA methylation, but deciphering the regulation of individual copies has been...
5.
6.
Doucet A, Cristofari G
Cancer Discov
. 2023 Dec;
13(12):2502-2504.
PMID: 38084092
LINE-1 retrotransposons are frequently active in epithelial tumors. In a new study, Taylor, Wu and colleagues now describe that one of the proteins encoded by LINE-1 elements, ORF1p, is detected...
7.
Yakhou L, Azogui A, Gupta N, Richard Albert J, Miura F, Ferry L, et al.
Nucleic Acids Res
. 2023 Aug;
51(19):10292-10308.
PMID: 37650637
Epigenetic mechanisms are essential to establish and safeguard cellular identities in mammals. They dynamically regulate the expression of genes, transposable elements and higher-order chromatin structures. Consequently, these chromatin marks are...
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9.
Gupta N, Yakhou L, Richard Albert J, Azogui A, Ferry L, Kirsh O, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(8):1105-1118.
PMID: 37488355
In mammals, only the zygote and blastomeres of the early embryo are totipotent. This totipotency is mirrored in vitro by mouse '2-cell-like cells' (2CLCs), which appear at low frequency in...
10.
Weber V, Doucet A, Cristofari G
Methods Mol Biol
. 2022 Nov;
2607:329-353.
PMID: 36449169
Transposable element insertions can have broad effects on gene expression, ranging from new regulatory functions to pathogenic consequences by transplanting new cis-regulating elements or perturbing existing ones. Genetic manipulation of...