Pascale Lesage
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Explore the profile of Pascale Lesage including associated specialties, affiliations and a list of published articles.
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30
Citations
514
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Recent Articles
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Lesage P, Brasset E, Cristofari G, Gilbert C, Mazel D, Rebollo R, et al.
Mob DNA
. 2024 Oct;
15(1):25.
PMID: 39462418
From April 20 to 23, 2024, three hundred ten researchers from around the world gathered in Saint-Malo, France, at the fourth International Congress on Transposable Elements (ICTE 2024), to present...
3.
Lesage P, Maxwell P
Proc Natl Acad Sci U S A
. 2023 Aug;
120(35):e2311419120.
PMID: 37590432
No abstract available.
4.
Nguyen P, Huecas S, Asif-Laidin A, Plaza-Pegueroles A, Capuzzi B, Palmic N, et al.
Nat Commun
. 2023 Mar;
14(1):1729.
PMID: 36977686
The yeast Ty1 retrotransposon integrates upstream of genes transcribed by RNA polymerase III (Pol III). Specificity of integration is mediated by an interaction between the Ty1 integrase (IN1) and Pol...
5.
Barkova A, Adhya I, Conesa C, Asif-Laidin A, Bonnet A, Rabut E, et al.
Mob DNA
. 2022 Nov;
13(1):26.
PMID: 36401307
Background: Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile...
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Bonnet A, Chaput C, Palmic N, Palancade B, Lesage P
PLoS Genet
. 2021 Nov;
17(11):e1009889.
PMID: 34723966
Beyond their canonical function in nucleocytoplasmic exchanges, nuclear pore complexes (NPCs) regulate the expression of protein-coding genes. Here, we have implemented transcriptomic and molecular methods to specifically address the impact...
8.
Nguyen P, Conesa C, Rabut E, Bragagnolo G, Gouzerh C, Fernandez-Tornero C, et al.
J Biol Chem
. 2021 Aug;
297(4):101093.
PMID: 34416236
Long-terminal repeat (LTR) retrotransposons are genetic elements that, like retroviruses, replicate by reverse transcription of an RNA intermediate into a complementary DNA (cDNA) that is next integrated into the host...
9.
Martinat C, Cormier A, Tobaly-Tapiero J, Palmic N, Casartelli N, Mahboubi B, et al.
Nat Commun
. 2021 Jul;
12(1):4582.
PMID: 34321470
SAMHD1 is a cellular triphosphohydrolase (dNTPase) proposed to inhibit HIV-1 reverse transcription in non-cycling immune cells by limiting the supply of the dNTP substrates. Yet, phosphorylation of T592 downregulates SAMHD1...
10.
Bonnet A, Lesage P
Curr Genet
. 2021 Feb;
67(3):347-357.
PMID: 33590295
Transposable elements are ubiquitous in genomes. Their successful expansion depends in part on their sites of integration in their host genome. In Saccharomyces cerevisiae, evolution has selected various strategies to...