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Erik C Andersen

Explore the profile of Erik C Andersen including associated specialties, affiliations and a list of published articles. Areas
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Articles 110
Citations 2842
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Recent Articles
31.
Gibson S, Ness-Cohn E, Andersen E
Int J Parasitol Drugs Drug Resist . 2022 Nov; 20():89-96. PMID: 36332489
Parasitic nematode infections cause an enormous global burden to both humans and livestock. Resistance to the limited arsenal of anthelmintic drugs used to combat these infections is widespread, including benzimidazole...
32.
Zhang G, Wang Y, Andersen E
Genome Res . 2022 Oct; 32(10):1852-1861. PMID: 36195344
Short tandem repeats (STRs) represent an important class of genetic variation that can contribute to phenotypic differences. Although millions of single nucleotide variants (SNVs) and short indels have been identified...
33.
Wit J, Workentine M, Redman E, Laing R, Stevens L, Cotton J, et al.
Int J Parasitol . 2022 Sep; 52(10):677-689. PMID: 36113620
Genome-wide methods offer a powerful approach to detect signatures of drug selection. However, limited availability of suitable reference genomes and the difficulty of obtaining field populations with well-defined, distinct drug...
34.
Widmayer S, Crombie T, Nyaanga J, Evans K, Andersen E
Toxicology . 2022 Aug; 479:153292. PMID: 35995124
The genetic variability of toxicant responses among indisviduals in humans and mammalian models requires practically untenable sample sizes to create comprehensive chemical hazard risk evaluations. To address this need, tractable...
35.
Nyaanga J, Andersen E
G3 (Bethesda) . 2022 Aug; 12(10). PMID: 35961034
Growth rate and body size are complex traits that contribute to the fitness of organisms. The identification of loci that underlie differences in these traits provides insights into the genetic...
36.
Fox B, Ponomarova O, Lee Y, Zhang G, Giese G, Walker M, et al.
Nature . 2022 Jul; 607(7919):571-577. PMID: 35794472
Individuals can exhibit differences in metabolism that are caused by the interplay of genetic background, nutritional input, microbiota and other environmental factors. It is difficult to connect differences in metabolism...
37.
Pallotto L, Dilks C, Park Y, Smit R, Lu B, Gopalakrishnan C, et al.
Genetics . 2022 Jun; 221(4). PMID: 35731216
Parasitic nematodes are major human and agricultural pests, and benzimidazoles are amongst the most important broad-spectrum anthelmintic drug class used for their control. Benzimidazole resistance is now widespread in many...
38.
Webster A, Chitrakar R, Powell M, Chen J, Fisher K, Tanny R, et al.
Elife . 2022 Jun; 11. PMID: 35727141
Starvation resistance is important to disease and fitness, but the genetic basis of its natural variation is unknown. Uncovering the genetic basis of complex, quantitative traits such as starvation resistance...
39.
Zhang G, Roberto N, Lee D, Hahnel S, Andersen E
Nat Commun . 2022 Jun; 13(1):3462. PMID: 35710766
Phenotypic variation in organism-level traits has been studied in Caenorhabditis elegans wild strains, but the impacts of differences in gene expression and the underlying regulatory mechanisms are largely unknown. Here,...
40.
Crombie T, Chikuturudzi C, Cook D, Andersen E
MicroPubl Biol . 2022 Jun; 2022. PMID: 35647500
Chemotaxis assays are used extensively to study behavioral responses of nematodes to environmental cues. These assays result in a chemotaxis index (CI) that denotes the behavioral response of a population...