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Lewis Stevens

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Articles 35
Citations 733
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Recent Articles
1.
Kirangwa J, Laetsch D, King E, Stevens L, Blaxter M, Holovachov O, et al.
Sci Rep . 2024 Nov; 14(1):29513. PMID: 39604390
Hox genes are central to metazoan body plan formation, patterning and evolution, playing a critical role in cell fate decisions early in embryonic development in invertebrates and vertebrates. While the...
2.
Kieninger M, Stevens L, Collins J, Blaxter M
Wellcome Open Res . 2024 Aug; 9:292. PMID: 39114493
We present a genome assembly of the free-living nematode (Nematoda; Chromadorea; Rhabditida; Rhabditidae). The genome sequence is 51.3 megabases in span. Most of the assembly is scaffolded into six chromosomal...
3.
Harriss L, Stevens L, Rayner C, Simpson G, Annels N, Frampton A
Expert Rev Gastroenterol Hepatol . 2024 May; 18(6):223-226. PMID: 38818792
Araki H, Tazawa H, Kanaya N, et al. Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer. Mol Ther Oncolytics. 2022;27:3-13.Pancreatic ductal adenocarcinoma...
4.
Peona V, Martelossi J, Almojil D, Bocharkina J, Brannstrom I, Brown M, et al.
Mob DNA . 2024 May; 15(1):10. PMID: 38711146
Background: The advancement of sequencing technologies results in the rapid release of hundreds of new genome assemblies a year providing unprecedented resources for the study of genome evolution. Within this...
5.
Wright C, Stevens L, Mackintosh A, Lawniczak M, Blaxter M
Nat Ecol Evol . 2024 Feb; 8(4):777-790. PMID: 38383850
Chromosomes are a central unit of genome organization. One-tenth of all described species on Earth are butterflies and moths, the Lepidoptera, which generally possess 31 chromosomes. However, some species display...
6.
Stevens L, Kieninger M, Chan B, Wood J, Gonzalez de La Rosa P, Allen J, et al.
PLoS Genet . 2024 Jan; 20(1):e1011116. PMID: 38227589
Heteromorphic sex chromosomes are usually thought to have originated from a pair of autosomes that acquired a sex-determining locus and subsequently stopped recombining, leading to degeneration of the sex-limited chromosome....
7.
Stevens L, Martinez-Ugalde I, King E, Wagah M, Absolon D, Bancroft R, et al.
Nat Commun . 2023 Nov; 14(1):7776. PMID: 38012132
Host-parasite interactions exert strong selection pressures on the genomes of both host and parasite. These interactions can lead to negative frequency-dependent selection, a form of balancing selection that is hypothesised...
8.
Moya N, Stevens L, Miller I, Sokol C, Galindo J, Bardas A, et al.
BMC Genomics . 2023 Aug; 24(1):486. PMID: 37626289
Background: The nematode Caenorhabditis briggsae has been used as a model in comparative genomics studies with Caenorhabditis elegans because of their striking morphological and behavioral similarities. However, the potential of...
9.
Shatilovich A, Gade V, Pippel M, Hoffmeyer T, Tchesunov A, Stevens L, et al.
PLoS Genet . 2023 Jul; 19(7):e1010798. PMID: 37498820
Some organisms in nature have developed the ability to enter a state of suspended metabolism called cryptobiosis when environmental conditions are unfavorable. This state-transition requires execution of a combination of...
10.
Lee D, Fox B, Fajardo Palomino D, Panda O, Tenjo F, Koury E, et al.
Proc Natl Acad Sci U S A . 2023 Jun; 120(26):e2221150120. PMID: 37339205
From bacterial quorum sensing to human language, communication is essential for social interactions. Nematodes produce and sense pheromones to communicate among individuals and respond to environmental changes. These signals are...