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Toxicology

Toxicology is a peer-reviewed scientific journal that focuses on the study of adverse effects of chemicals on living organisms. It covers a wide range of topics including toxic substances, their mechanisms of action, and their impact on human health and the environment. The journal publishes original research articles, reviews, and commentaries, providing a platform for researchers and experts to share their findings and insights in the field of toxicology.

Details
Abbr. Toxicology
Publisher Elsevier
Start 1973
End Continuing
Frequency Thirty three no. a year, 1999-
p-ISSN 0300-483X
e-ISSN 1879-3185
Country Ireland
Language English
Specialty Toxicology
Metrics
h-index / Ranks: 995 176
SJR / Ranks: 3733 1014
CiteScore / Ranks: 2975 6.90
JIF / Ranks: 1882 4.5
Recent Articles
1.
Acharya N, Richburg J
Toxicology . 2025 Mar; :154118. PMID: 40089264
Mono-(2-ethylhexyl) phthalate (MEHP) is a metabolite of the diester parent compound Di(2-ethylhexyl) phthalate (DEHP), a widespread environmental toxicant known for its harmful effects on Sertoli cells and the subsequent loss...
2.
Zhang H, Lin F, Lin B, Sun X, Zheng Q, Gao R, et al.
Toxicology . 2025 Mar; :154117. PMID: 40086502
Bisphenol S (BPS) is widely used in the production of food containers and children's toys and is known to have endocrine-disrupting effects linked to various cancers; however, its role in...
3.
Liu J, Chen X, Chen C, Wu J, Xie F, Li J, et al.
Toxicology . 2025 Mar; :154107. PMID: 40064458
mRNA-based technology has been evaluated in a variety of clinical trials for the rapid control and prevention of emergencies and therapeutic indications. HC009 is a mRNA-based vaccine encoding the full-length...
4.
Jochum K, Miccoli A, Sommersdorf C, Poetz O, Braeuning A, Tralau T, et al.
Toxicology . 2025 Mar; 514:154104. PMID: 40054833
New Approach Methodologies (NAMs), including cell culture and multi-level omics analyses, are promising alternatives to animal testing. To become useable for risk assessment purposes, they have to be applicable for...
5.
Hac P, Okabayashi S, Tsuboi M, Cieslik B, Konieczka P
Toxicology . 2025 Mar; :154092. PMID: 40054832
Smoking-related diseases represent a substantial global health challenge, particularly given the direct inhalation of smoke into the vulnerable respiratory system. This method of consumption presents a challenge in classifying smoking...
6.
Liu S, He Y, Jin L, Shi S, Zhang J, Xie W, et al.
Toxicology . 2025 Mar; 514:154109. PMID: 40049282
Silica exposure-induced airway epithelial-mesenchymal transition (EMT) is a critical pathological process in pulmonary fibrosis. This study investigated the role of NLRP3 inflammasome, glycolysis, and histone lactylation in silica-induced EMT of...
7.
Wibowo A, Chong K, Tayara H
Toxicology . 2025 Mar; 514:154108. PMID: 40032152
Drug-induced liver injury (DILI) toxicity is a condition when drugs have a destructive effect on the liver organ. The prediction of this toxicity becomes crucial in the drug development process...
8.
Seifert S, Siewert K, Curato C, Sonnenburg A, Fritsch N, Peiser M, et al.
Toxicology . 2025 Mar; 514:154100. PMID: 40024515
According to Regulation (EC) No 1272/2008, plant protection products (PPPs) can be classified for skin sensitisation by either considering the full formulation or the individual components. For a fraction of...
9.
Yu Z, Su H, Gao Z, Chen Y, Zhang Y, Duan W, et al.
Toxicology . 2025 Mar; 514:154099. PMID: 40024514
Dioxins, a group of environmental pollutants, can cause developmental toxicity through interaction with the aromatic hydrocarbon receptor (AHR). Retinoic acid (RA) functions via binding to retinoic acid receptor (RAR)/retinoid X...
10.
Qin J, Yu B, Zhou Y, Huang W, Luo Z, Chen R, et al.
Toxicology . 2025 Mar; :154106. PMID: 40023215
Sintilimab, an immune checkpoint inhibitor, and acetaminophen (APAP), a common analgesic, have been implicated in hepatotoxicity. However, their combined effect on liver injury remains understudied. This study investigated the exacerbating...