Leonid Kruglyak
Overview
Explore the profile of Leonid Kruglyak including associated specialties, affiliations and a list of published articles.
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131
Citations
14717
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Recent Articles
1.
Boocock J, Alexander N, Alamo Tapia L, Walter-McNeill L, Patel S, Munugala C, et al.
Elife
. 2025 Mar;
13.
PMID: 40073070
Expression quantitative trait loci (eQTLs) provide a key bridge between noncoding DNA sequence variants and organismal traits. The effects of eQTLs can differ among tissues, cell types, and cellular states,...
2.
Zdraljevic S, Walter-McNeill L, Bruni G, Bloom J, Leighton D, Collins J, et al.
bioRxiv
. 2024 Nov;
PMID: 39605437
Toxin-antidote elements (TAs) are selfish DNA sequences that bias their transmission to the next generation. TAs typically consist of two linked genes: a toxin and an antidote. The toxin kills...
3.
Zeevi D, Ben Yehuda A, Nathan D, Zangen D, Kruglyak L
Children (Basel)
. 2024 Aug;
11(8).
PMID: 39201851
For the past 50 years, standard guidelines have recommended the use of sex-adjusted mid-parental height to predict a child's final height. Here, we studied the accuracy of this procedure. We...
4.
Boocock J, Alexander N, Alamo Tapia L, Walter-McNeill L, Patel S, Munugala C, et al.
bioRxiv
. 2023 Dec;
PMID: 38106186
Expression quantitative trait loci (eQTLs) provide a key bridge between noncoding DNA sequence variants and organismal traits. The effects of eQTLs can differ among tissues, cell types, and cellular states,...
5.
Guo L, Kruglyak L
Physiol Genomics
. 2023 Aug;
55(11):479-486.
PMID: 37642275
Although there are more than 10,000 reptile species, and reptiles have historically contributed to our understanding of biology, genetics research into class Reptilia has lagged compared with other animals. Here,...
6.
Kruglyak L, Beyer A, Bloom J, Grossbach J, Lieberman T, Mancuso C, et al.
Nature
. 2023 Apr;
616(7957):E8-E9.
PMID: 37076734
No abstract available.
7.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L
MicroPubl Biol
. 2023 Mar;
2023.
PMID: 36879982
Identification of the genetic basis of phenotypic variation within species remains challenging. In species with low recombination rates, such as , genomic regions linked to a phenotype of interest by...
8.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L
bioRxiv
. 2023 Jan;
PMID: 36711988
Identification of the genetic basis of phenotypic variation within species remains challenging. In species with low recombination rates, such as , genomic regions linked to a phenotype of interest by...
9.
Swichkow C, Bloom J, Kruglyak L
PLoS Biol
. 2022 Dec;
20(12):e3001911.
PMID: 36525401
Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic...
10.
Dhindsa R, Wang Q, Vitsios D, Burren O, Hu F, DiCarlo J, et al.
Am J Hum Genet
. 2022 Dec;
109(12):2105-2109.
PMID: 36459978
Synonymous mutations change the DNA sequence of a gene without affecting the amino acid sequence of the encoded protein. Although some synonymous mutations can affect RNA splicing, translational efficiency, and...