Stefan Zdraljevic
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Explore the profile of Stefan Zdraljevic including associated specialties, affiliations and a list of published articles.
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28
Citations
804
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Recent Articles
1.
Zdraljevic S, Walter-McNeill L, Bruni G, Bloom J, Leighton D, Collins J, et al.
bioRxiv
. 2024 Nov;
PMID: 39605437
Toxin-antidote elements (TAs) are selfish DNA sequences that bias their transmission to the next generation. TAs typically consist of two linked genes: a toxin and an antidote. The toxin kills...
2.
Wit J, Dilks C, Zhang G, Kim Guisbert K, Zdraljevic S, Guisbert E, et al.
PLoS One
. 2023 Aug;
18(8):e0286473.
PMID: 37561720
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans and other animals. Caenorhabditis elegans is an established model to investigate anthelmintics used to treat roundworms. In...
3.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L
MicroPubl Biol
. 2023 Mar;
2023.
PMID: 36879982
Identification of the genetic basis of phenotypic variation within species remains challenging. In species with low recombination rates, such as , genomic regions linked to a phenotype of interest by...
4.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L
bioRxiv
. 2023 Jan;
PMID: 36711988
Identification of the genetic basis of phenotypic variation within species remains challenging. In species with low recombination rates, such as , genomic regions linked to a phenotype of interest by...
5.
Fox B, Ponomarova O, Lee Y, Zhang G, Giese G, Walker M, et al.
Nature
. 2022 Jul;
607(7919):571-577.
PMID: 35794472
Individuals can exhibit differences in metabolism that are caused by the interplay of genetic background, nutritional input, microbiota and other environmental factors. It is difficult to connect differences in metabolism...
6.
Widmayer S, Evans K, Zdraljevic S, Andersen E
G3 (Bethesda)
. 2022 May;
12(7).
PMID: 35536194
Quantitative genetics in Caenorhabditis elegans seeks to identify naturally segregating genetic variants that underlie complex traits. Genome-wide association studies scan the genome for individual genetic variants that are significantly correlated...
7.
Crombie T, Battlay P, Tanny R, Evans K, Buchanan C, Cook D, et al.
Mol Ecol
. 2022 Feb;
31(8):2327-2347.
PMID: 35167162
The nematode Caenorhabditis elegans is among the most widely studied organisms, but relatively little is known about its natural ecology. Genetic diversity is low across much of the globe but...
8.
Gilbert K, Zdraljevic S, Cook D, Cutter A, Andersen E, Baer C
Genetics
. 2021 Nov;
220(1).
PMID: 34791202
The distribution of fitness effects (DFE) for new mutations is one of the most theoretically important but difficult to estimate properties in population genetics. A crucial challenge to inferring the...
9.
Lee D, Zdraljevic S, Stevens L, Wang Y, Tanny R, Crombie T, et al.
Nat Ecol Evol
. 2021 Apr;
5(6):794-807.
PMID: 33820969
Across diverse taxa, selfing species have evolved independently from outcrossing species thousands of times. The transition from outcrossing to selfing decreases the effective population size, effective recombination rate and heterozygosity...
10.
Ben-David E, Boocock J, Guo L, Zdraljevic S, Bloom J, Kruglyak L
Elife
. 2021 Mar;
10.
PMID: 33734084
Genetic regulation of gene expression underlies variation in disease risk and other complex traits. The effect of expression quantitative trait loci (eQTLs) varies across cell types; however, the complexity of...