Ellen A Bernstein
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Explore the profile of Ellen A Bernstein including associated specialties, affiliations and a list of published articles.
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38
Citations
763
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Recent Articles
1.
Saito S, Cao D, Bernstein E, Shibata T, Jones A, Rios A, et al.
Cell Mol Immunol
. 2025 Feb;
22(3):243-259.
PMID: 39910334
Increased expression of angiotensin-converting enzyme (ACE) by myeloid lineage cells strongly increases the immune activity of these cells, as observed in ACE10/10 mice, which exhibit a marked increase in antitumor...
2.
Bernstein K, Cao D, Shibata T, Saito S, Bernstein E, Nishi E, et al.
J Biol Chem
. 2024 May;
300(6):107388.
PMID: 38763333
As part of the classical renin-angiotensin system, the peptidase angiotensin-converting enzyme (ACE) makes angiotensin II which has myriad effects on systemic cardiovascular function, inflammation, and cellular proliferation. Less well known...
3.
Saito S, Cao D, Bernstein E, Jones A, Rios A, Hoshi A, et al.
Res Sq
. 2024 May;
PMID: 38746124
An upregulation of angiotensin-converting enzyme (ACE) expression strengthens the immune activity of myeloid lineage cells as a natural functional regulation mechanism in our immunity. ACE10/10 mice, possessing increased ACE expression...
4.
Shibata T, Bhat S, Cao D, Saito S, Bernstein E, Nishi E, et al.
J Biol Chem
. 2023 Nov;
300(1):105486.
PMID: 37992807
Testis angiotensin-converting enzyme (tACE) plays a critical role in male fertility, but the mechanism is unknown. By using ACE C-domain KO (CKO) mice which lack tACE activity, we found that...
5.
Cao D, Saito S, Xu L, Fan W, Li X, Ahmed F, et al.
Front Immunol
. 2023 Nov;
14:1278383.
PMID: 37928535
The pathogenesis of atherosclerosis is defined by impaired lipid handling by macrophages which increases intracellular lipid accumulation. This dysregulation of macrophages triggers the accumulation of apoptotic cells and chronic inflammation...
6.
Cao D, Khan Z, Li X, Saito S, Bernstein E, Victor A, et al.
Cardiovasc Res
. 2023 May;
119(9):1825-1841.
PMID: 37225143
Aims: The metabolic failure of macrophages to adequately process lipid is central to the aetiology of atherosclerosis. Here, we examine the role of macrophage angiotensin-converting enzyme (ACE) in a mouse...
7.
Shibata T, Cao D, Dar T, Ahmed F, Bhat S, Veiras L, et al.
Cancers (Basel)
. 2022 Nov;
14(21).
PMID: 36358691
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive disease with poor prognosis, which is mainly due to drug resistance. The biology determining the response to chemo-radiotherapy in...
8.
Veiras L, Bernstein E, Cao D, Okwan-Duodu D, Khan Z, Gibb D, et al.
Circ Res
. 2022 May;
131(1):59-73.
PMID: 35574842
Background: Chronic renal inflammation has been widely recognized as a major promoter of several forms of high blood pressure including salt-sensitive hypertension. In diabetes, IL (interleukin)-6 induces salt sensitivity through...
9.
Cao D, Veiras L, Ahmed F, Shibata T, Bernstein E, Okwan-Duodu D, et al.
Peptides
. 2022 Feb;
152:170769.
PMID: 35182689
Angiotensin converting enzyme (ACE) is well known for its role producing the vasoconstrictor angiotensin II and ACE inhibitors are commonly used for treating hypertension and cardiovascular disease. However, ACE has...
10.
Cao D, Giani J, Veiras L, Bernstein E, Okwan-Duodu D, Ahmed F, et al.
Sci Transl Med
. 2021 Jul;
13(604).
PMID: 34321319
Angiotensin-converting enzyme inhibitors (ACEIs) are used by millions of patients to treat hypertension, diabetic kidney disease, and heart failure. However, these patients are often at increased risk of infection. To...