Ellen A Bernstein
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Explore the profile of Ellen A Bernstein including associated specialties, affiliations and a list of published articles.
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38
Citations
763
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Recent Articles
11.
Giani J, Veiras L, Shen J, Bernstein E, Cao D, Okwan-Duodu D, et al.
Mol Cell Endocrinol
. 2021 Mar;
529:111257.
PMID: 33781839
The observation that all components of the renin angiotensin system (RAS) are expressed in the kidney and the fact that intratubular angiotensin (Ang) II levels greatly exceed the plasma concentration...
12.
Veiras L, Shen J, Bernstein E, Regis G, Cao D, Okwan-Duodu D, et al.
J Am Soc Nephrol
. 2021 Mar;
32(5):1131-1149.
PMID: 33731332
Background: Hypertension is considered a major risk factor for the progression of diabetic kidney disease. Type 2 diabetes is associated with increased renal sodium reabsorption and salt-sensitive hypertension. Clinical studies...
13.
Peng Z, Liu C, Victor A, Cao D, Veiras L, Bernstein E, et al.
Oncoimmunology
. 2021 Feb;
10(1):1870811.
PMID: 33537175
Granulocytes are key players in cancer metastasis. While tumor-induced expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the metastatic...
14.
Dominici F, Veiras L, Shen J, Bernstein E, Quiroga D, Steckelings U, et al.
Br J Pharmacol
. 2020 Aug;
177(20):4766-4781.
PMID: 32851652
Background And Purpose: The AT receptor plays a role in metabolism by opposing the actions triggered by the AT receptors. Activation of AT receptors has been shown to enhance insulin...
15.
Cao D, Saito S, Veiras L, Okwan-Duodu D, Bernstein E, Giani J, et al.
Cell Mol Biol Lett
. 2020 Jun;
25:31.
PMID: 32508938
Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a potent vasoconstrictor. Because of its...
16.
Veiras L, Cao D, Saito S, Peng Z, Bernstein E, Shen J, et al.
Curr Hypertens Rep
. 2020 Jan;
22(1):4.
PMID: 31916032
To review recent studies exploring how myeloid cell overexpression of angiotensin-converting enzyme (ACE) affects the immune response and to formulate an approach for considering the effectiveness of inflammation in cardiovascular...
17.
Cao D, Spivia W, Veiras L, Khan Z, Peng Z, Jones A, et al.
J Biol Chem
. 2019 Dec;
295(5):1369-1384.
PMID: 31871049
Angiotensin-converting enzyme (ACE) affects blood pressure. In addition, ACE overexpression in myeloid cells increases their immune function. Using MS and chemical analysis, we identified marked changes of intermediate metabolites in...
18.
Okwan-Duodu D, Weiss D, Peng Z, Veiras L, Cao D, Saito S, et al.
Biochem Biophys Res Commun
. 2019 Oct;
520(3):573-579.
PMID: 31615657
Background: Macrophages are ubiquitous in all stages of atherosclerosis, exerting tremendous impact on lesion progression and plaque stability. Because macrophages in atherosclerotic plaques express angiotensin-converting enzyme (ACE), current dogma posits...
19.
Zhao T, Li Y, Liu X, Xia S, Shi P, Li L, et al.
Sci Immunol
. 2019 Jun;
4(36).
PMID: 31253642
The cause of most hypertensive disease is unclear, but inflammation appears critical in disease progression. However, how elevated blood pressure initiates inflammation is unknown, as are the effects of high...
20.
Semis M, Gugiu G, Bernstein E, Bernstein K, Kalkum M
Anal Chem
. 2019 Apr;
91(10):6440-6453.
PMID: 31021607
Angiotensin-converting enzyme (ACE) converts angiotensin I into the potent vasoconstrictor angiotensin II, which regulates blood pressure. However, ACE activity is also essential for other physiological functions, presumably through processing of...