Xiao Z Shen
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Explore the profile of Xiao Z Shen including associated specialties, affiliations and a list of published articles.
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53
Citations
1697
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Recent Articles
1.
Wang Z, Hu Y, Shen X, Tan W
Cell Death Dis
. 2024 Oct;
15(10):760.
PMID: 39424788
Langerhans cells (LCs) are resident dendritic cells in the epidermis and their roles in presenting antigens derived from microorganisms present in the skin has been well appreciated. However, it is...
2.
Wei B, Cheng G, Bi Q, Lu C, Sun Q, Li L, et al.
Immunity
. 2024 Aug;
57(9):2030-2042.e8.
PMID: 39116878
Hypertension is usually accompanied by elevated sympathetic tonicity, but how sympathetic hyperactivity is triggered is not clear. Recent advances revealed that microglia-centered neuroinflammation contributes to sympathetic excitation in hypertension. In...
3.
He J, Cao Y, Zhu Q, Wang X, Cheng G, Wang Q, et al.
Immunity
. 2023 Dec;
57(1):106-123.e7.
PMID: 38159573
When the filtrate of the glomerulus flows through the renal tubular system, various microscopic sediment particles, including mineral crystals, are generated. Dislodging these particles is critical to ensuring the free...
4.
Weng Y, Chen N, Zhang R, He J, Ding X, Cheng G, et al.
Brain Behav Immun
. 2023 Nov;
115:705-717.
PMID: 37992789
Pericyte is an indispensable cellular constituent of blood-brain barrier (BBB) and its homeostasis heavily rely on PDGFB-PDGFRβ signaling. However, the primary cellular sources of PDGFB in the central nervous system...
5.
Zhu Q, Xiao L, Cheng G, He J, Yin C, Wang L, et al.
Kidney Int
. 2023 May;
104(2):324-333.
PMID: 37224917
The kidney is critical in controlling salt and water balance, with the interstitium involved with a variety of components including immune cells in steady state. However, the roles of resident...
6.
Nie W, Li M, Liu B, Zhang Y, Wang Y, Wang J, et al.
Cell Mol Life Sci
. 2022 Nov;
79(12):595.
PMID: 36394649
Fibrosis is a relentlessly progressive and irreversible cause of organ damage, as in chronic kidney disease (CKD), but its underlying mechanisms remain elusive. We found that a circular RNA, circPTPN14,...
7.
Bi Q, Wang C, Cheng G, Chen N, Wei B, Liu X, et al.
Immunity
. 2022 Jul;
55(8):1466-1482.e9.
PMID: 35863346
Although many studies have addressed the regulatory circuits affecting neuronal activities, local non-synaptic mechanisms that determine neuronal excitability remain unclear. Here, we found that microglia prevented overactivation of pre-sympathetic neurons...
8.
Zhu Q, He J, Cao Y, Liu X, Nie W, Han F, et al.
Front Immunol
. 2022 Apr;
13:805420.
PMID: 35359928
The interstitium of kidney involves a variety of components including resident immune cells, in particular mononuclear phagocytes. However, many proposed markers for distinguishing macrophages or dendritic cells are, in fact,...
9.
Wang Z, Zhao W, Cao Y, Liu Y, Sun Q, Shi P, et al.
Front Immunol
. 2020 Dec;
11:603187.
PMID: 33343575
The underlying mechanisms of wound healing are complex but inflammation is one of the determining factors. Besides its traditional role in combating against infection upon injury, the characteristics and magnitude...
10.
Liu X, Wei B, Bi Q, Sun Q, Li L, He J, et al.
Neurotox Res
. 2020 Mar;
38(1):27-37.
PMID: 32198706
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the accumulation of Lewy bodies and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpC). MPTP is widely used...