David P Sester
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Explore the profile of David P Sester including associated specialties, affiliations and a list of published articles.
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42
Citations
1751
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Recent Articles
11.
Thygesen S, Takizawa K, Robertson A, Sester D, Stacey K
Immunol Cell Biol
. 2018 Jul;
97(1):17-28.
PMID: 30052286
Inflammasomes are protein complexes activated by infection and cellular stress that promote caspase-1 activation and subsequent inflammatory cytokine processing and cell death. It has been anticipated that inflammasome activity contributes...
12.
Sester D, Zamoshnikova A, Thygesen S, Vajjhala P, Cridland S, Schroder K, et al.
Curr Protoc Immunol
. 2016 Aug;
114:14.40.1-14.40.29.
PMID: 27479658
Inflammasomes are large protein complexes formed in response to cellular stresses that are platforms for recruitment and activation of caspase 1. Central to most inflammasome functions is the adapter molecule...
13.
14.
Thygesen S, Sester D, Cridland S, Wilton S, Stacey K
Immunol Cell Biol
. 2016 Feb;
94(5):520-4.
PMID: 26833024
Inflammasomes are molecular complexes activated by infection and cellular stress, leading to caspase-1 activation and subsequent interleukin-1β (IL-1β) processing and cell death. The autoimmune NZB mouse strain does not express...
15.
Vitak N, Hume D, Chappell K, Sester D, Stacey K
Dev Comp Immunol
. 2016 Feb;
59:145-52.
PMID: 26828392
Responses to cytosolic DNA can protect against both infectious organisms and the mutagenic effect of DNA integration. Recognition of invading DNA is likely to be fundamental to eukaryotic cellular life,...
16.
Stacey K, Idris A, Sagulenko V, Vitak N, Sester D
Methods Mol Biol
. 2016 Jan;
1390:93-106.
PMID: 26803624
Cytosolic DNA can indicate infection and induces type I interferon (IFN) and AIM2 inflammasome responses. Characterization of these responses has required introduction of DNA into the cytosol of macrophages by...
17.
18.
Vajjhala P, Lu A, Brown D, Pang S, Sagulenko V, Sester D, et al.
J Biol Chem
. 2015 Oct;
290(49):29217-30.
PMID: 26468282
Inflammasomes mediate inflammatory and cell death responses to pathogens and cellular stress signals via activation of procaspases-1 and -8. During inflammasome assembly, activated receptors of the NLR or PYHIN family...
19.
Modhiran N, Watterson D, Muller D, Panetta A, Sester D, Liu L, et al.
Sci Transl Med
. 2015 Sep;
7(304):304ra142.
PMID: 26355031
Complications arising from dengue virus infection include potentially fatal vascular leak, and severe disease has been linked with excessive immune cell activation. An understanding of the triggers of this activation...
20.
Sester D, Sagulenko V, Thygesen S, Cridland J, Loi Y, Cridland S, et al.
J Immunol
. 2015 Jun;
195(3):1233-41.
PMID: 26116505
Inflammasomes are protein complexes that promote caspase activation, resulting in processing of IL-1β and cell death, in response to infection and cellular stresses. Inflammasomes have been anticipated to contribute to...