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Simon O Cridland

Explore the profile of Simon O Cridland including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 133
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Recent Articles
1.
Sester D, Zamoshnikova A, Thygesen S, Vajjhala P, Cridland S, Schroder K, et al.
Curr Protoc Immunol . 2016 Aug; 114:14.40.1-14.40.29. PMID: 27479658
Inflammasomes are large protein complexes formed in response to cellular stresses that are platforms for recruitment and activation of caspase 1. Central to most inflammasome functions is the adapter molecule...
2.
Thygesen S, Sester D, Cridland S, Wilton S, Stacey K
Immunol Cell Biol . 2016 Feb; 94(5):520-4. PMID: 26833024
Inflammasomes are molecular complexes activated by infection and cellular stress, leading to caspase-1 activation and subsequent interleukin-1β (IL-1β) processing and cell death. The autoimmune NZB mouse strain does not express...
3.
Vajjhala P, Lu A, Brown D, Pang S, Sagulenko V, Sester D, et al.
J Biol Chem . 2015 Oct; 290(49):29217-30. PMID: 26468282
Inflammasomes mediate inflammatory and cell death responses to pathogens and cellular stress signals via activation of procaspases-1 and -8. During inflammasome assembly, activated receptors of the NLR or PYHIN family...
4.
Sester D, Sagulenko V, Thygesen S, Cridland J, Loi Y, Cridland S, et al.
J Immunol . 2015 Jun; 195(3):1233-41. PMID: 26116505
Inflammasomes are protein complexes that promote caspase activation, resulting in processing of IL-1β and cell death, in response to infection and cellular stresses. Inflammasomes have been anticipated to contribute to...
5.
Papathanasiou P, Tunningley R, Pattabiraman D, Ye P, Gonda T, Whittle B, et al.
Blood . 2010 Jul; 116(26):5849-58. PMID: 20610815
Identification of genes that regulate the development, self-renewal, and differentiation of stem cells is of vital importance for understanding normal organogenesis and cancer; such knowledge also underpins regenerative medicine. Here...
6.
Cridland S, Keys J, Papathanasiou P, Perkins A
Blood Cells Mol Dis . 2009 May; 43(2):149-55. PMID: 19443245
Indian hedgehog (Ihh) has been reported to stimulate haematopoiesis ex vivo. In this study we studied the consequences of loss of function of Ihh for murine haematopoietic development. Ihh has...
7.
Keys J, Tallack M, Hodge D, Cridland S, David R, Perkins A
Br J Haematol . 2006 Oct; 136(1):150-7. PMID: 17069580
Alpha haemoglobin stabilising protein (AHSP) binds free alpha-globin chains and plays an important role in the protection of red cells, particularly during beta-thalassaemia. Murine ASHP was discovered as a GATA-1...