David I Rhodes
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Explore the profile of David I Rhodes including associated specialties, affiliations and a list of published articles.
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21
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211
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Recent Articles
1.
Parker B, Rhodes D, OBrien C, Rodda A, Cameron N
Acta Biomater
. 2021 Sep;
135:64-86.
PMID: 34492374
Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete...
2.
Dalton N, Gordon C, Boyle T, Vandegraaf N, Deadman J, Rhodes D, et al.
Org Biomol Chem
. 2016 May;
14(25):6010-23.
PMID: 27225230
From library screening of synthetic antimicrobial peptides, an O-allyltyrosine-based tripeptide was identified to possess inhibitory activity against HIV-1 integrase (IN) exhibiting an IC50 value of 17.5 μM in a combination...
3.
Nugraha A, Hilou A, Vandegraaff N, Rhodes D, Haritakun R, Keller P
Nat Prod Res
. 2015 Feb;
29(20):1954-8.
PMID: 25699473
Phytochemical studies of the previously unexplored stem of Boerhavia erecta from Burkina Faso, resulted in the isolation of an unreported glycoside 4, 2,3-dihydroxypropylbenzoate-3-O-β-[4″-methoxy] glucuronide as well as seven known glycosides...
4.
Vashi A, White J, McLean K, Neethling W, Rhodes D, Ramshaw J, et al.
J Biomed Mater Res A
. 2014 Oct;
103(6):1999-2005.
PMID: 25266083
The present study has evaluated a commercial pericardial material for its capacity to assist as a natural extracellular matrix (ECM) patch for the delivery and retention of mesenchymal stem cells...
5.
Wielens J, Headey S, Rhodes D, Mulder R, Dolezal O, Deadman J, et al.
J Biomol Screen
. 2012 Nov;
18(2):147-59.
PMID: 23139382
Fragment screening is becoming widely accepted as a technique to identify hit compounds for the development of novel lead compounds. In neighboring laboratories, we have recently, and independently, performed a...
6.
Bremner J, Keller P, Pyne S, Robertson M, Sakthivel K, Somphol K, et al.
Beilstein J Org Chem
. 2012 Sep;
8:1265-70.
PMID: 23019457
The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic group variations in the C-terminal amino acid component, is described. Moderate to good activity was seen against...
7.
Peat T, Rhodes D, Vandegraaff N, Le G, Smith J, Clark L, et al.
PLoS One
. 2012 Jul;
7(7):e40147.
PMID: 22808106
A fragment-based screen against human immunodeficiency virus type 1 (HIV) integrase led to a number of compounds that bound to the lens epithelium derived growth factor (LEDGF) binding site of...
8.
Rhodes D, Peat T, Vandegraaff N, Jeevarajah D, Newman J, Martyn J, et al.
Chembiochem
. 2011 Aug;
12(15):2311-5.
PMID: 21850718
An optimised method of solution cyclisation gave us access to a series of peptides including SLKIDNLD (2). We investigated the crystallographic complexes of the HIV integrase (HIV-IN) catalytic core domain...
9.
Robertson M, Bremner J, Coates J, Deadman J, Keller P, Pyne S, et al.
Eur J Med Chem
. 2011 Jul;
46(9):4201-11.
PMID: 21757269
The synthesis of eleven novel antibacterial agents is reported. The structures are based on a C(2)-symmetric binaphthyl scaffold which holds two identical chains consisting of a short linker, a basic...
10.
Rhodes D, Peat T, Vandegraaff N, Jeevarajah D, Le G, Jones E, et al.
Antivir Chem Chemother
. 2011 May;
21(4):155-68.
PMID: 21602613
Background: HIV-1 integrase is a clinically validated therapeutic target for the treatment of HIV-1 infection, with one approved therapeutic currently on the market. This enzyme represents an attractive target for...