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Paul A Keller

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Articles 100
Citations 819
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Recent Articles
1.
Ali S, McCosker P, Willis A, Pyne S, Richardson C, Bremner J, et al.
Molecules . 2024 Sep; 29(17). PMID: 39275089
The reaction of indigo with two equivalents of the electrophile ethyl bromoacetate with caesium carbonate as a base result in the formation of structurally complex polyheterocyclics, including a fused spiroimidazole...
2.
Eka Ningrum N, Cahyaning Rahamjnhyu D, Dianhar H, Wongso H, Keller P, Satia Nugraha A
Chem Biodivers . 2024 Jul; 21(10):e202400794. PMID: 38997231
Natural occurring peroxides are interesting bioprospecting targets due to their molecular structural diversity and the wide range of pharmacological activities. In this systematic review, a total of 123 peroxide compounds...
3.
Cun W, Keller P, Pyne S
Microorganisms . 2024 Jun; 12(6). PMID: 38930588
is a Gram-positive, spore-forming anaerobic bacterial pathogen that causes severe gastrointestinal infection in humans. This review provides background information on infection and the pathogenesis and toxigenicity of . The risk...
4.
Perry M, Curic M, Scott A, Ritmejeryte E, Rahayu D, Keller P, et al.
Life (Basel) . 2024 Jun; 14(6). PMID: 38929693
Recent studies have shown that seagrasses could possess potential applications in the treatment of inflammatory disorders. Five seagrass species (, , , , and ) from the Great Barrier Reef...
5.
Cun W, Bate C, Srikhanta Y, Hutton M, Webb C, Revitt-Mills S, et al.
J Med Chem . 2023 Dec; 67(1):450-466. PMID: 38112278
With the aim of discovering small molecule inhibitors of the sporulation process in , we prepared a series of C-7 α-(4-substituted-1-1,2,3-triazol-1-yl)acetamide analogues of cefotetan, a known inhibitor of the sporulation-specific...
6.
Cun W, Keller P, Pyne S
Molecules . 2023 Nov; 28(21). PMID: 37959756
The aim of this project was to develop a synthetic protocol for the preparation of a cephamycin scaffold that would readily allow the synthesis of its analogues with variations at...
7.
Satia Nugraha A, Firli L, Rani D, Hidayatiningsih A, Lestari N, Wongso H, et al.
Nat Prod Bioprospect . 2023 Oct; 13(1):38. PMID: 37843645
The archipelagic country of Indonesia is populated by the densest marine biodiversity in the world which has created strong global interest and is valued by both Indigenous and European settlements...
8.
Shiels O, Menti-Platten M, Bokosi F, Burns B, Keaveney S, Keller P, et al.
Anal Chem . 2023 Oct; 95(42):15472-15476. PMID: 37830912
An experimental platform is reported that allows for the online characterization of photochemical reactions by coupling a continuous flow photoreactor, equipped with LED light irradiation and a dual-tipped ESI source,...
9.
Rani D, Wongso H, Purwoko R, Winarto N, Shalas A, Triatmoko B, et al.
Phytochemistry . 2023 Oct; 216:113881. PMID: 37827225
The Indonesian archipelago is home to the second largest biodiversity in the world and is inhabited by more than 300 ethnic groups with a total population of more than 270...
10.
Wongso H, Ono M, Yamasaki T, Kumata K, Higuchi M, Zhang M, et al.
RSC Med Chem . 2023 May; 14(5):858-868. PMID: 37252097
The pyridinyl-butadienyl-benzothiazole (PBB3 15) scaffold was used to develop tau ligands with improved and properties for imaging applications to provide insights into the etiology and characteristics of Alzheimer's disease. The...