Christian A J Vosshenrich
Overview
Explore the profile of Christian A J Vosshenrich including associated specialties, affiliations and a list of published articles.
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34
Citations
2772
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Recent Articles
1.
Scarno G, Mazej J, Laffranchi M, Di Censo C, Mattiola I, Candelotti A, et al.
Proc Natl Acad Sci U S A
. 2023 Sep;
120(40):e2306761120.
PMID: 37756335
Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1) require signal transducer and activator of transcription 4 (STAT4) to elicit rapid effector responses and protect against pathogens. By...
2.
Dupont M, Guillemot V, Campagne P, Serafini N, Marie S, Montagutelli X, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(10).
PMID: 33649222
Natural killer (NK) cells are innate effectors armed with cytotoxic and cytokine-secreting capacities whose spontaneous antitumor activity is key to numerous immunotherapeutic strategies. However, current mouse models fail to mirror...
3.
Dupont M, Vosshenrich C
Methods Mol Biol
. 2018 Nov;
1884:161-176.
PMID: 30465202
Over the last decades, it has been established that the immune system is crucial for the impediment of cancer development by recognizing and destroying transformed cells. This process has been...
4.
Verrier T, Satoh-Takayama N, Serafini N, Marie S, Di Santo J, Vosshenrich C
J Immunol
. 2016 May;
196(11):4731-8.
PMID: 27183613
Group 3 innate lymphoid cells (ILC3) actively participate in mucosal defense and homeostasis through prompt secretion of IL-17A, IL-22, and IFN-γ. Reports identify two ILC3 lineages: a CCR6(+)T-bet(-) subset that...
5.
Chea S, Perchet T, Petit M, Verrier T, Guy-Grand D, Banchi E, et al.
Sci Signal
. 2016 May;
9(426):ra45.
PMID: 27141929
The Notch signaling pathway is conserved throughout evolution, and it controls various processes, including cell fate determination, differentiation, and proliferation. Innate lymphoid cells (ILCs) are lymphoid cells lacking antigen receptors...
6.
Serafini N, Vosshenrich C, Di Santo J
Nat Rev Immunol
. 2015 Jun;
15(7):415-28.
PMID: 26065585
Innate lymphoid cells (ILCs) are a recently described family of lymphoid effector cells that have important roles in immune defence, inflammation and tissue remodelling. It has been proposed that ILCs...
7.
Sepulveda F, Maschalidi S, Vosshenrich C, Garrigue A, Kurowska M, Menasche G, et al.
Blood
. 2014 Dec;
125(9):1427-34.
PMID: 25525117
The impairment of cytotoxic activity of lymphocytes disturbs immune surveillance and leads to the development of hemophagocytic lymphohistiocytic syndrome (HLH). Although cytotoxic T lymphocyte (CTL) control of HLH development is...
8.
Merzoug L, Marie S, Satoh-Takayama N, Lesjean S, Albanesi M, Luche H, et al.
Eur J Immunol
. 2014 Aug;
44(11):3380-91.
PMID: 25142413
To study gene functions specifically in NKp46+ cells we developed novel Cre mice allowing for conditional gene targeting in cells expressing Ncr1 (encoding NKp46). We generated transgenic Ncr1(greenCre) mice carrying...
9.
Serafini N, Klein Wolterink R, Satoh-Takayama N, Xu W, Vosshenrich C, Hendriks R, et al.
J Exp Med
. 2014 Jan;
211(2):199-208.
PMID: 24419270
Group 3 innate lymphoid cells (ILC3) include IL-22-producing NKp46(+) cells and IL-17A/IL-22-producing CD4(+) lymphoid tissue inducerlike cells that express RORγt and are implicated in protective immunity at mucosal surfaces. Whereas...
10.
Vallese D, Negroni E, Duguez S, Ferry A, Trollet C, Aamiri A, et al.
Mol Ther
. 2013 Aug;
21(10):1950-7.
PMID: 23975040
The development of innovative therapeutic strategies for muscular dystrophies, particularly cell-based approaches, is still a developing field. Although positive results have been obtained in animal models, they have rarely been...