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Christian A J Vosshenrich

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Recent Articles
11.
Klein Wolterink R, Serafini N, van Nimwegen M, Vosshenrich C, de Bruijn M, Fonseca Pereira D, et al.
Proc Natl Acad Sci U S A . 2013 Jun; 110(25):10240-5. PMID: 23733962
Group 2 innate lymphoid cells (ILC2s; also called nuocytes, innate helper cells, or natural helper cells) provide protective immunity during helminth infection and play an important role in influenza-induced and...
12.
Vosshenrich C, Di Santo J
Curr Opin Immunol . 2013 Mar; 25(2):130-8. PMID: 23490162
In recent years we have witnessed a blooming interest in innate lymphoid cell (ILC) biology thanks to the discovery of novel lineages of ILC that are phenotypically and functionally distinct...
13.
Satoh-Takayama N, Lesjean-Pottier S, Sawa S, Vosshenrich C, Eberl G, Di Santo J
Eur J Immunol . 2011 Feb; 41(3):780-6. PMID: 21341264
The natural cytotoxicity receptor NKp46 is an activating receptor expressed by several distinct innate lymphoid cell (ILC) subsets, including NK cells, some γδ T cells and intestinal RORγt(+) IL-22(+) cells...
14.
Elkabets M, Ribeiro V, Dinarello C, Ostrand-Rosenberg S, Di Santo J, Apte R, et al.
Eur J Immunol . 2010 Nov; 40(12):3347-57. PMID: 21110318
Chronic inflammation is associated with promotion of malignancy and tumor progression. Many tumors enhance the accumulation of myeloid-derived suppressor cells (MDSC), which contribute to tumor progression and growth by suppressing...
15.
Klein Wolterink R, Garcia-Ojeda M, Vosshenrich C, Hendriks R, Di Santo J
Immunol Rev . 2010 Oct; 238(1):126-37. PMID: 20969589
T lymphocytes depend on the thymic microenvironment for initiation of the T-cell developmental program. As the progenitors in the thymus have lost the capacity to self-renew, this process depends on...
16.
Ribeiro V, Hasan M, Wilson A, Boucontet L, Pereira P, Lesjean-Pottier S, et al.
J Immunol . 2010 Oct; 185(9):4993-7. PMID: 20889548
Although NK cells in the mouse are thought to develop in the bone marrow, a small population of NK cells in the thymus has been shown to derive from a...
17.
Di Santo J, Vosshenrich C, Satoh-Takayama N
Curr Opin Immunol . 2010 Jun; 22(4):435-41. PMID: 20573491
The mucosal barrier comprises a layered defense system including physio-chemical and immunological strategies to contain commensal microflora while protecting the host against potential pathogens. In contrast to the clearly established...
18.
Satoh-Takayama N, Lesjean-Pottier S, Vieira P, Sawa S, Eberl G, Vosshenrich C, et al.
J Exp Med . 2010 Feb; 207(2):273-80. PMID: 20142427
The natural cytotoxicity receptor NKp46 (encoded by Ncr1) was recently shown to identify a subset of noncytotoxic, Rag-independent gut lymphocytes that express the transcription factor Rorc, produce interleukin (IL)-22, and...
19.
Satoh-Takayama N, Dumoutier L, Lesjean-Pottier S, Ribeiro V, Mandelboim O, Renauld J, et al.
J Immunol . 2009 Oct; 183(10):6579-87. PMID: 19846871
Natural cytotoxicity receptors (including NKp30, NKp44, and NKp46 in humans and NKp46 in mice) are type I transmembrane proteins that signal NK cell activation via ITAM-containing adapter proteins in response...
20.
Satoh-Takayama N, Vosshenrich C, Lesjean-Pottier S, Sawa S, Lochner M, Rattis F, et al.
Immunity . 2008 Dec; 29(6):958-70. PMID: 19084435
Natural killer (NK) cells are innate lymphocytes with spontaneous antitumor activity, and they produce interferon-gamma (IFN-gamma) that primes immune responses. Whereas T helper cell subsets differentiate from naive T cells...