Chad R Hancock
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Explore the profile of Chad R Hancock including associated specialties, affiliations and a list of published articles.
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38
Citations
963
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Recent Articles
21.
Stallings M, Cardon B, Hardman J, Bliss T, Brunson S, Hart C, et al.
Nutr Res
. 2014 Apr;
34(4):308-17.
PMID: 24774067
Selenium (Se) has been implicated as a micronutrient that decreases adenosine monophosphate-activated protein kinase (AMPK) signaling and may increase diabetes risk by reducing insulin sensitivity. Soy isoflavones (IF) are estrogen-like...
22.
Hardman S, Hall D, Cabrera A, Hancock C, Thomson D
Exp Gerontol
. 2014 Apr;
55:120-8.
PMID: 24747582
Sarcopenia is characterized by increased skeletal muscle atrophy due in part to alterations in muscle metabolism. AMP-activated protein kinase (AMPK) is a master regulator of skeletal muscle metabolic pathways which...
23.
Bridgewater L, Mayo J, Evanson B, Whitt M, Dean S, Yates J, et al.
Biomed Res Int
. 2013 Dec;
2013:125492.
PMID: 24369527
We recently reported a novel form of BMP2, designated nBMP2, which is translated from an alternative downstream start codon and is localized to the nucleus rather than secreted from the...
24.
Henriksen B, Curtis M, Fillmore N, Cardon B, Thomson D, Hancock C
Diabetol Metab Syndr
. 2013 Jun;
5:29.
PMID: 23725555
Background: High fat feeding increases hepatic fat accumulation and is associated with hepatic insulin resistance. AMP Activated Protein Kinase (AMPK) is thought to inhibit lipid synthesis by the acute inhibition...
25.
Merrill J, Thomson D, Hardman S, Hepworth S, Willie S, Hancock C
Nutr Metab (Lond)
. 2012 Nov;
9(1):104.
PMID: 23171474
Unlabelled: Background: As a cellular energy sensor, the 5'AMP-activated protein kinase (AMPK) is activated in response to energy stresses such as hypoxia and muscle contraction. To determine effects of iron...
26.
Erickson K, Smith M, Anthonymuthu T, Evanson M, Brassfield E, Hodson A, et al.
Diabetol Metab Syndr
. 2012 Nov;
4(1):45.
PMID: 23134616
Unlabelled: Background: The worldwide prevalence of obesity has lead to increased efforts to find therapies to treat obesity-related pathologies. Ceramide is a well-established mediator of several health problems that arise...
27.
Quiner T, Nakken H, Mason B, Lephart E, Hancock C, Christensen M
J Nutr
. 2011 Oct;
141(12):2159-65.
PMID: 22031663
The effects of supplemental Se in rodent models may depend upon composition of the basal diet to which it is added. Wild-type male littermates of Transgenic Adenocarcinoma of Mouse Prostate...
28.
Frier B, Hancock C, Little J, Fillmore N, Bliss T, Thomson D, et al.
J Appl Physiol (1985)
. 2011 Jun;
111(3):688-95.
PMID: 21700896
Receptor interacting protein 1 (RIP140) has recently been demonstrated to be a key player in the regulation of skeletal muscle mitochondrial content. We have shown that β-guanadinopropionic acid (β-GPA) feeding...
29.
Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance
Han D, Hancock C, Jung S, Higashida K, Kim S, Holloszy J
PLoS One
. 2011 May;
6(5):e19739.
PMID: 21589859
Background: It has been proposed that muscle insulin resistance in type 2 diabetes is due to a selective decrease in the components of the mitochondrial electron transport chain and results...
30.
Hancock C, Han D, Higashida K, Kim S, Holloszy J
FASEB J
. 2010 Nov;
25(2):785-91.
PMID: 21048043
It has been reported that 30% calorie restriction (CR) for 3 mo results in large increases in mitochondrial biogenesis in heart, brain, liver, and adipose tissue, with concomitant increases in...