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Caleb Lareau

Explore the profile of Caleb Lareau including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1510
Followers 0
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Recent Articles
1.
LaFave L, Kartha V, Ma S, Meli K, Del Priore I, Lareau C, et al.
Cancer Cell . 2025 Mar; PMID: 40054468
No abstract available.
2.
Yu K, Abou-Mrad Z, Torkenczy K, Schulze I, Gantchev J, Baquer G, et al.
bioRxiv . 2025 Mar; PMID: 40027797
Malignant gliomas follow two distinct natural histories: high grade tumors such as glioblastoma, or lower grade tumors with a propensity to transform into high grade disease. Despite differences in tumor...
3.
Nuno K, Azizi A, Koehnke T, Lareau C, Ediriwickrema A, Corces M, et al.
Elife . 2024 Apr; 13. PMID: 38647535
Relapse of acute myeloid leukemia (AML) is highly aggressive and often treatment refractory. We analyzed previously published AML relapse cohorts and found that 40% of relapses occur without changes in...
4.
Bucktrout S, Banovich N, Butterfield L, Cimen-Bozkus C, Giles J, Good Z, et al.
Nat Med . 2024 Feb; 30(5):1505. PMID: 38317023
No abstract available.
5.
Doan A, Mueller K, Chen A, Rouin G, Daniel B, Lattin J, et al.
Res Sq . 2023 Nov; PMID: 37986944
Poor CAR T persistence limits CAR T cell therapies for B cell malignancies and solid tumors. The expression of memory-associated genes such as (protein name TCF1) is linked to response...
6.
Lareau C
Nat Biotechnol . 2023 May; 41(12):1690-1691. PMID: 37198441
No abstract available.
7.
Tousley A, Rotiroti M, Labanieh L, Rysavy L, Kim W, Lareau C, et al.
Nature . 2023 Mar; 615(7952):507-516. PMID: 36890224
Although chimeric antigen receptor (CAR) T cells have altered the treatment landscape for B cell malignancies, the risk of on-target, off-tumour toxicity has hampered their development for solid tumours because...
8.
Panditharatna E, Marques J, Wang T, Trissal M, Liu I, Jiang L, et al.
Cancer Discov . 2022 Oct; 12(12):2880-2905. PMID: 36305736
Significance: Epigenetic dysregulation is at the core of H3K27M-glioma tumorigenesis. Here, we identify the BRG1-BAF complex as a critical regulator of enhancer and transcription factor landscapes, which maintain H3K27M glioma...
9.
Bucktrout S, Banovich N, Butterfield L, Cimen-Bozkus C, Giles J, Good Z, et al.
Nat Med . 2022 Sep; 28(9):1761-1764. PMID: 36127419
No abstract available.
10.
King H, Wells K, Shipony Z, Kathiria A, Wagar L, Lareau C, et al.
Sci Immunol . 2021 Oct; 6(64):eabh3768. PMID: 34623901
The germinal center (GC) response is critical for both effective adaptive immunity and establishing peripheral tolerance by limiting autoreactive B cells. Dysfunction in these processes can lead to defective immune...