Travis Law
Overview
Explore the profile of Travis Law including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
1571
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0
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Recent Articles
1.
LaFave L, Kartha V, Ma S, Meli K, Del Priore I, Lareau C, et al.
Cancer Cell
. 2025 Mar;
PMID: 40054468
No abstract available.
2.
Puram S, Mints M, Pal A, Qi Z, Reeb A, Gelev K, et al.
Nat Genet
. 2023 Apr;
55(4):640-650.
PMID: 37012457
Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive and HPV-negative oropharyngeal tumors,...
3.
Larson R, Kann M, Bailey S, Haradhvala N, Montero Llopis P, Bouffard A, et al.
Nature
. 2022 Apr;
604(7906):563-570.
PMID: 35418687
Chimeric antigen receptor (CAR) therapy has had a transformative effect on the treatment of haematologic malignancies, but it has shown limited efficacy against solid tumours. Solid tumours may have cell-intrinsic...
4.
Ouspenskaia T, Law T, Clauser K, Klaeger S, Sarkizova S, Aguet F, et al.
Nat Biotechnol
. 2021 Oct;
40(2):209-217.
PMID: 34663921
Tumor-associated epitopes presented on MHC-I that can activate the immune system against cancer cells are typically identified from annotated protein-coding regions of the genome, but whether peptides originating from novel...
5.
Qi Z, Liu Y, Mints M, Mullins R, Sample R, Law T, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33799782
Complexities in cell-type composition have rightfully led to skepticism and caution in the interpretation of bulk transcriptomic analyses. Recent studies have shown that deconvolution algorithms can be utilized to computationally...
6.
Ma S, Zhang B, LaFave L, Earl A, Chiang Z, Hu Y, et al.
Cell
. 2020 Oct;
183(4):1103-1116.e20.
PMID: 33098772
Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process precluding a...
7.
LaFave L, Kartha V, Ma S, Meli K, Del Priore I, Lareau C, et al.
Cancer Cell
. 2020 Jul;
38(2):212-228.e13.
PMID: 32707078
Regulatory networks that maintain functional, differentiated cell states are often dysregulated in tumor development. Here, we use single-cell epigenomics to profile chromatin state transitions in a mouse model of lung...
8.
Sarkizova S, Klaeger S, Le P, Li L, Oliveira G, Keshishian H, et al.
Nat Biotechnol
. 2019 Dec;
38(2):199-209.
PMID: 31844290
Prediction of HLA epitopes is important for the development of cancer immunotherapies and vaccines. However, current prediction algorithms have limited predictive power, in part because they were not trained on...
9.
Ludwig L, Lareau C, Ulirsch J, Christian E, Muus C, Li L, et al.
Cell
. 2019 Mar;
176(6):1325-1339.e22.
PMID: 30827679
Lineage tracing provides key insights into the fate of individual cells in complex organisms. Although effective genetic labeling approaches are available in model systems, in humans, most approaches require detection...
10.
Chihara N, Madi A, Kondo T, Zhang H, Acharya N, Singer M, et al.
Nature
. 2018 Jun;
558(7710):454-459.
PMID: 29899446
The expression of co-inhibitory receptors, such as CTLA-4 and PD-1, on effector T cells is a key mechanism for ensuring immune homeostasis. Dysregulated expression of co-inhibitory receptors on CD4 T...