Vinay K Kartha
Overview
Explore the profile of Vinay K Kartha including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
1341
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Recent Articles
1.
LaFave L, Kartha V, Ma S, Meli K, Del Priore I, Lareau C, et al.
Cancer Cell
. 2025 Mar;
PMID: 40054468
No abstract available.
2.
Hu Y, Horlbeck M, Zhang R, Ma S, Shrestha R, Kartha V, et al.
Nature
. 2025 Jan;
638(8051):779-786.
PMID: 39843737
Cis-regulatory elements (CREs) control gene expression and are dynamic in their structure and function, reflecting changes in the composition of diverse effector proteins over time. However, methods for measuring the...
3.
Cheong J, Ravishankar A, Sharma S, Parkhurst C, Grassmann S, Wingert C, et al.
Cell
. 2023 Aug;
186(18):3882-3902.e24.
PMID: 37597510
Inflammation can trigger lasting phenotypes in immune and non-immune cells. Whether and how human infections and associated inflammation can form innate immune memory in hematopoietic stem and progenitor cells (HSPC)...
4.
Hu Y, Ma S, Kartha V, Duarte F, Horlbeck M, Zhang R, et al.
bioRxiv
. 2023 Apr;
PMID: 37034577
-regulatory elements control gene expression and are dynamic in their structure, reflecting changes to the composition of diverse effector proteins over time. Here we sought to connect the structural changes...
5.
Kartha V, Duarte F, Hu Y, Ma S, Chew J, Lareau C, et al.
Cell Genom
. 2022 Oct;
2(9).
PMID: 36204155
Cells require coordinated control over gene expression when responding to environmental stimuli. Here we apply scATAC-seq and single-cell RNA sequencing (scRNA-seq) in resting and stimulated human blood cells. Collectively, we...
6.
Concepcion C, Ma S, LaFave L, Bhutkar A, Liu M, DeAngelo L, et al.
Cancer Discov
. 2021 Sep;
12(2):562-585.
PMID: 34561242
/ encodes for one of two mutually exclusive ATPases present in mammalian SWI/SNF chromatin remodeling complexes and is frequently mutated in human lung adenocarcinoma. However, the functional consequences of mutation...
7.
Ma S, Zhang B, LaFave L, Earl A, Chiang Z, Hu Y, et al.
Cell
. 2020 Oct;
183(4):1103-1116.e20.
PMID: 33098772
Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process precluding a...
8.
LaFave L, Kartha V, Ma S, Meli K, Del Priore I, Lareau C, et al.
Cancer Cell
. 2020 Jul;
38(2):212-228.e13.
PMID: 32707078
Regulatory networks that maintain functional, differentiated cell states are often dysregulated in tumor development. Here, we use single-cell epigenomics to profile chromatin state transitions in a mouse model of lung...
9.
Chandler K, Alamoud K, Stahl V, Nguyen B, Kartha V, Bais M, et al.
Mol Omics
. 2020 Mar;
16(3):195-209.
PMID: 32203567
Epidermal growth factor receptor (EGFR) is a major driver of head and neck cancer, a devastating malignancy with a major sub-site in the oral cavity manifesting as oral squamous cell...
10.
Lareau C, Duarte F, Chew J, Kartha V, Burkett Z, Kohlway A, et al.
Nat Biotechnol
. 2019 Jun;
37(8):916-924.
PMID: 31235917
Recent technical advancements have facilitated the mapping of epigenomes at single-cell resolution; however, the throughput and quality of these methods have limited their widespread adoption. Here we describe a high-quality...