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Benjamin J Reed

Explore the profile of Benjamin J Reed including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 337
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Recent Articles
1.
Traeger A, Reed B, OConnor D, Hoffmann T, Machado G, Bonner C, et al.
BMJ Open . 2018 Feb; 8(2):e019470. PMID: 29440161
Introduction: Little is known about how to reduce unnecessary imaging for low back pain. Understanding clinician, patient and general public beliefs about imaging is critical to developing strategies to reduce...
2.
Neal A, Rountree A, Kernan K, Van Yserloo B, Zhang H, Reed B, et al.
Biochem J . 2016 Oct; 473(23):4443-4456. PMID: 27729543
A real-time method to measure intracellular hydrogen peroxide (HO) would be very impactful in characterizing rapid changes that occur in physiologic and pathophysiologic states. Current methods do not provide the...
3.
Oeser M, Amen T, Nadel C, Bradley A, Reed B, Jones R, et al.
PLoS Genet . 2016 Jan; 12(1):e1005809. PMID: 26800527
Cells are often exposed to physical or chemical stresses that can damage the structures of essential biomolecules. Stress-induced cellular damage can become deleterious if not managed appropriately. Rapid and adaptive...
4.
Reed B, Locke M, Gardner R
J Biol Chem . 2015 Jul; 290(33):20601-12. PMID: 26149687
In the canonical view of protein function, it is generally accepted that the three-dimensional structure of a protein determines its function. However, the past decade has seen a dramatic growth...
5.
Richardson L, Reed B, Charette J, Freed E, Fredrickson E, Locke M, et al.
Cell Rep . 2012 Aug; 2(2):372-85. PMID: 22902402
Eukaryotic ribosome biogenesis requires hundreds of trans-acting factors and dozens of RNAs. Although most factors required for ribosome biogenesis have been identified, little is known about their regulation. Here, we...
6.
Jung S, Reed B, Sweet I
Am J Physiol Endocrinol Metab . 2009 Jul; 297(3):E717-27. PMID: 19584201
Calcium (Ca(2+)) influx is required for the sustained secretion of insulin and is accompanied by a large rate of energy usage. We hypothesize that the energy usage reflects a process...
7.
Cummings B, Digitale E, Stanhope K, Graham J, Baskin D, Reed B, et al.
Am J Physiol Regul Integr Comp Physiol . 2008 Oct; 295(6):R1782-93. PMID: 18832086
The prevalence of type 2 diabetes (T2DM) is increasing, creating a need for T2DM animal models for the study of disease pathogenesis, prevention, and treatment. The purpose of this project...
8.
Gilbert M, Jung S, Reed B, Sweet I
J Biol Chem . 2008 Jul; 283(36):24334-42. PMID: 18593707
The aim of the study was to test whether the source of intracellular calcium (Ca2+) is a determinant of beta cell function. We hypothesized that elevations in cytosolic Ca2+ caused...
9.
Mecklenburgh K, Walmsley S, Cowburn A, Wiesener M, Reed B, Upton P, et al.
Blood . 2002 Sep; 100(8):3008-16. PMID: 12351415
Neutrophil apoptosis represents a major mechanism involved in the resolution of acute inflammation. In contrast to the effect of hypoxia observed in many other cell types, oxygen deprivation, as we...
10.
Cowburn A, Cadwallader K, Reed B, Farahi N, Chilvers E
Blood . 2002 Sep; 100(7):2607-16. PMID: 12239175
Phosphoinositide 3-kinase (PI3-kinase)-dependent phosphorylation of the proapoptotic Bcl-2 family member Bad has been proposed as an important regulator of apoptotic cell death. To understand the importance of this pathway in...