Angela Goytain
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Explore the profile of Angela Goytain including associated specialties, affiliations and a list of published articles.
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22
Citations
681
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Recent Articles
1.
Goytain A, Ng T
Head Neck Pathol
. 2024 Oct;
18(1):116.
PMID: 39466450
Purpose: Salivary gland tumors include numerous subtypes that vary from benign to highly aggressive, with many showing overlapping histopathological features that can make diagnosis challenging. Most subtypes express driver fusion...
2.
Hofvander J, Qiu A, Lee K, Bilenky M, Carles A, Cao Q, et al.
bioRxiv
. 2024 May;
PMID: 38798672
Synovial sarcoma (SyS) is an aggressive soft-tissue malignancy characterized by a pathognomonic chromosomal translocation leading to the formation of the SS18::SSX fusion oncoprotein. SS18::SSX associates with mammalian BAF complexes suggesting...
3.
Goytain A, Chang K, Goh J, Nielsen T, Ng T
J Mol Diagn
. 2022 Dec;
25(2):121-131.
PMID: 36503147
Sarcomas are a diverse group of tumors, with >70 subtypes in the current World Health Organization classification, each with distinct biological behavior requiring specific clinical management. A significant portion of...
4.
Asleh K, Lluch A, Goytain A, Barrios C, Wang X, Torrecillas L, et al.
Clin Cancer Res
. 2022 Nov;
29(2):389-400.
PMID: 36346687
Purpose: Predictive biomarkers for capecitabine benefit in triple-negative breast cancer (TNBC) have been recently proposed using samples from phase III clinical trials, including non-basal phenotype and biomarkers related to angiogenesis,...
5.
Wang X, Goytain A, Dickson B, Nielsen T
Genes Chromosomes Cancer
. 2022 Jan;
61(6):332-345.
PMID: 35064596
Sarcomas are cancers of mesenchymal origin with the potential to arise in diverse anatomic locations. With over 80 subtypes, which often demonstrate overlapping morphologies, sarcomas frequently require ancillary testing to...
6.
Wang X, Wang X, Hsu A, Goytain A, Ng T, Nielsen T
J Mol Diagn
. 2020 Dec;
23(3):274-284.
PMID: 33346147
Histologic examination neither reliably distinguishes benign lipomas from atypical lipomatous tumor/well-differentiated liposarcoma, nor dedifferentiated liposarcoma from other pleomorphic sarcomas, entities with different prognoses and management. Molecular confirmation of pathognomonic 12q13-15...
7.
Goytain A, Ng T
Methods Mol Biol
. 2019 Nov;
2079:125-139.
PMID: 31728967
NanoString nCounter is a multiplex nucleic acid hybridization technology that enables reliable and reproducible assessment of the expression of up to 800 genes or 228 gene fusions in 12 samples...
8.
Jones M, Williamson L, Topham J, Lee M, Goytain A, Ho J, et al.
Clin Cancer Res
. 2019 May;
25(15):4674-4681.
PMID: 31068372
Purpose: Gene fusions involving neuregulin 1 () have been noted in multiple cancer types and have potential therapeutic implications. Although varying results have been reported in other cancer types, the...
9.
Chapman E, Skalova A, Ptakova N, Martinek P, Goytain A, Tucker T, et al.
Am J Surg Pathol
. 2018 Jul;
42(9):1182-1189.
PMID: 29975250
We describe a novel gene fusion, EWSR1-CREM, identified in 3 cases of clear cell carcinoma (CCC) using anchored multiplex polymerase chain reaction, a next-generation sequencing-based technique. CCC is a low-grade...
10.
Chang K, Goytain A, Tucker T, Karsan A, Lee C, Nielsen T, et al.
J Mol Diagn
. 2017 Nov;
20(1):63-77.
PMID: 29104083
The NanoString nCounter assay is a high-throughput hybridization technique using target-specific probes that can be customized to test for numerous fusion transcripts in a single assay using RNA from formalin-fixed,...