Alexander Tarakhovsky
Overview
Explore the profile of Alexander Tarakhovsky including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
77
Citations
8026
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Tough D, Tak P, Tarakhovsky A, Prinjha R
Nat Rev Drug Discov
. 2016 Nov;
15(12):835-853.
PMID: 27765940
Immune-mediated diseases are clinically heterogeneous but they share genetic and pathogenic mechanisms. These diseases may develop from the interplay of genetic factors and environmental or lifestyle factors. Exposure to such...
12.
von Schimmelmann M, Feinberg P, Sullivan J, Ku S, Badimon A, Duff M, et al.
Nat Neurosci
. 2016 Aug;
19(10):1321-30.
PMID: 27526204
Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions. Neuronal specification is driven by transcriptional programs that are established...
13.
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation
Minnich M, Tagoh H, Bonelt P, Axelsson E, Fischer M, Cebolla B, et al.
Nat Immunol
. 2016 Jan;
17(3):331-43.
PMID: 26779602
The transcription factor Blimp-1 is necessary for the generation of plasma cells. Here we studied its functions in plasmablast differentiation by identifying regulated Blimp-1 target genes. Blimp-1 promoted the migration...
14.
Sullivan J, Badimon A, Schaefer U, Ayata P, Gray J, Chung C, et al.
J Exp Med
. 2015 Sep;
212(11):1771-81.
PMID: 26392221
Studies investigating the causes of autism spectrum disorder (ASD) point to genetic, as well as epigenetic, mechanisms of the disease. Identification of epigenetic processes that contribute to ASD development and...
15.
Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, et al.
Proc Natl Acad Sci U S A
. 2015 Jul;
112(32):E4448-57.
PMID: 26216992
Aire controls immunologic tolerance by inducing a battery of thymic transcripts encoding proteins characteristic of peripheral tissues. Its unusually broad effect is achieved by releasing RNA polymerase II paused just...
16.
Dobenecker M, Kim J, Marcello J, Fang T, Prinjha R, Bosselut R, et al.
J Exp Med
. 2015 Feb;
212(3):297-306.
PMID: 25687282
The fidelity of T cell immunity depends greatly on coupling T cell receptor signaling with specific T cell effector functions. Here, we describe a chromatin-based mechanism that enables integration of...
17.
Halper-Stromberg A, Lu C, Klein F, Horwitz J, Bournazos S, Nogueira L, et al.
Cell
. 2014 Aug;
158(5):989-999.
PMID: 25131989
Latent reservoirs of HIV-1-infected cells are refractory to antiretroviral therapies (ART) and remain the major barrier to curing HIV-1. Because latently infected cells are long-lived, immunologically invisible, and may undergo...
18.
Ruda V, Chandwani R, Sehgal A, Bogorad R, Akinc A, Charisse K, et al.
PLoS One
. 2014 Jul;
9(7):e101749.
PMID: 24992693
Argonaute 2 (Ago2) is the only mammalian Ago protein capable of mRNA cleavage. It has been reported that the activity of the short interfering RNA targeting coding sequence (CDS), but...
19.
Busslinger M, Tarakhovsky A
Cold Spring Harb Perspect Biol
. 2014 Jun;
6(6).
PMID: 24890513
Immunity relies on the heterogeneity of immune cells and their ability to respond to pathogen challenges. In the adaptive immune system, lymphocytes display a highly diverse antigen receptor repertoire that...
20.
Schaefer U, Ho J, Prinjha R, Tarakhovsky A
Cold Spring Harb Symp Quant Biol
. 2014 Apr;
78:81-90.
PMID: 24733380
One of the defining characteristics of human and animal viruses is their ability to suppress host antiviral responses. Viruses express proteins that impair the detection of viral nucleic acids by...