Aikaterini Alexaki
Overview
Explore the profile of Aikaterini Alexaki including associated specialties, affiliations and a list of published articles.
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30
Citations
943
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Recent Articles
1.
Kreidieh F, Tawbi H, Alexaki A, Borghaei H, Kandalaft L
Am Soc Clin Oncol Educ Book
. 2023 Jun;
43:e391278.
PMID: 37364224
Over the past decade, the advent of molecular techniques and deeper understanding of the tumor microenvironment (TME) have enabled the development of a multitude of immunotherapy targets and approaches. Despite...
2.
Katneni U, Alexaki A, Hunt R, Hamasaki-Katagiri N, Hettiarachchi G, Kames J, et al.
Blood Adv
. 2022 Apr;
6(13):3932-3944.
PMID: 35413099
Hemophilia B is a blood clotting disorder caused by deficient activity of coagulation factor IX (FIX). Multiple recombinant FIX proteins are currently approved to treat hemophilia B, and several gene...
3.
Meyer D, Kames J, Bar H, Komar A, Alexaki A, Ibla J, et al.
Genome Med
. 2021 Jul;
13(1):122.
PMID: 34321100
Background: Gene expression is highly variable across tissues of multi-cellular organisms, influencing the codon usage of the tissue-specific transcriptome. Cancer disrupts the gene expression pattern of healthy tissue resulting in...
4.
Holcomb D, Hamasaki-Katagiri N, Laurie K, Katneni U, Kames J, Alexaki A, et al.
Am J Hum Genet
. 2021 Jul;
108(8):1502-1511.
PMID: 34256028
Predicting the effect of a mutated gene before the onset of symptoms of genetic diseases would greatly facilitate diagnosis and potentiate early intervention. There have been myriad attempts to predict...
5.
Holcomb D, Alexaki A, Hernandez N, Hunt R, Laurie K, Kames J, et al.
PLoS Comput Biol
. 2021 Mar;
17(3):e1008805.
PMID: 33730015
Thrombosis is a recognized complication of Coronavirus disease of 2019 (COVID-19) and is often associated with poor prognosis. There is a well-recognized link between coagulation and inflammation, however, the extent...
6.
Alexaki A, Kames J, Hettiarachchi G, Athey J, Katneni U, Hunt R, et al.
F1000Res
. 2020 Oct;
9:174.
PMID: 33014344
Ribosome profiling provides the opportunity to evaluate translation kinetics at codon level resolution. Here, we describe ribosome profiling data, generated from two HEK293T cell lines. The ribosome profiling data are...
7.
Kames J, Holcomb D, Kimchi O, DiCuccio M, Hamasaki-Katagiri N, Wang T, et al.
Sci Rep
. 2020 Sep;
10(1):15643.
PMID: 32973171
As the SARS-CoV-2 pandemic is rapidly progressing, the need for the development of an effective vaccine is critical. A promising approach for vaccine development is to generate, through codon pair...
8.
Holcomb D, Alexaki A, Hernandez N, Laurie K, Kames J, Hamasaki-Katagiri N, et al.
bioRxiv
. 2020 Sep;
PMID: 32935103
Author Summary: Increased blood clotting, especially in the lungs, is a common complication of COVID-19. Infectious diseases cause inflammation which in turn can contribute to increased blood clotting. However, the...
9.
Katneni U, Alexaki A, Hunt R, Schiller T, DiCuccio M, Buehler P, et al.
Thromb Haemost
. 2020 Aug;
120(12):1668-1679.
PMID: 32838472
Coronavirus disease of 2019 (COVID-19) is the clinical manifestation of the respiratory infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While primarily recognized as a respiratory disease, it...
10.
Kames J, Holcomb D, Kimchi O, DiCuccio M, Hamasaki-Katagiri N, Wang T, et al.
bioRxiv
. 2020 Jun;
PMID: 32511300
As the SARS-CoV-2 pandemic is rapidly progressing, the need for the development of an effective vaccine is critical. A promising approach for vaccine development is to generate, through codon pair...