Brian Wigdahl
Overview
Explore the profile of Brian Wigdahl including associated specialties, affiliations and a list of published articles.
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Articles
156
Citations
2878
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Recent Articles
1.
Jones J, Gunderson C, Wigdahl B, Nonnemacher M
Epigenetics Chromatin
. 2025 Mar;
18(1):9.
PMID: 40055755
Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that infects multiple immune cell types and integrates into host cell DNA termed provirus. Under antiretroviral control, provirus in cells is...
2.
Garabet R, Dampier W, Tillman S, Malone K, Szep Z, Althoff A, et al.
J Neurovirol
. 2024 Jun;
30(4):423-433.
PMID: 38856821
Human immunodeficiency virus-associated neurocognitive disorders persist in the combination antiretroviral therapy era. CD4 nadir is a well-established predictor of cognition cross-sectionally, but its impact on longitudinal neurocognitive (NC) trajectories is...
3.
Gurrola T, Effah S, Sariyer I, Dampier W, Nonnemacher M, Wigdahl B
Front Microbiol
. 2024 May;
15():1393974.
PMID: 38812680
Human immunodeficiency virus type 1 (HIV-1) infection is well known as one of the most complex and difficult viral infections to cure. The difficulty in developing curative strategies arises in...
4.
Sutter J, Brettschneider J, Wigdahl B, Bruggeman P, Krebs F, Miller V
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612649
Herpes simplex virus type 1 (HSV-1) is a lifelong pathogen characterized by asymptomatic latent infection in the trigeminal ganglia (TG), with periodic outbreaks of cold sores caused by virus reactivation...
5.
Berman R, Dampier W, Nonnemacher M, Wigdahl B
Curr Opin HIV AIDS
. 2024 Mar;
19(3):150-156.
PMID: 38547339
Purpose Of Review: The leading gene editing strategy for a human immunodeficiency virus type 1 (HIV-1) cure involves the delivery of SaCas9 and two guide RNAs (gRNAs) in an adeno-associated...
6.
Haslund-Gourley B, Hou J, Woloszczuk K, Horn E, Dempsey G, Haddad E, et al.
EBioMedicine
. 2024 Jan;
100:104979.
PMID: 38266555
Background: Lyme disease is caused by the bacteria Borreliella burgdorferi sensu lato (Bb) transmitted to humans from the bite of an infected Ixodes tick. Current diagnostics for Lyme disease are...
7.
Dampier W, Berman R, Nonnemacher M, Wigdahl B
Front Genome Ed
. 2024 Jan;
5:1248982.
PMID: 38239625
The human immunodeficiency virus type 1 (HIV-1) pandemic has been slowed with the advent of anti-retroviral therapy (ART). However, ART is not a cure and as such has pushed the...
8.
Haslund-Gourley B, Woloszczuk K, Hou J, Connors J, Cusimano G, Bell M, et al.
Nat Commun
. 2024 Jan;
15(1):404.
PMID: 38195739
The glycosylation of IgG plays a critical role during human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing cytokine production. However, the role of IgM...
9.
Haslund-Gourley B, Woloszcuk K, Hou J, Connors J, Cusimano G, Bell M, et al.
Res Sq
. 2023 Jul;
PMID: 37398192
The glycosylation of IgG plays a critical role during human SARS-CoV-2, activating immune cells and inducing cytokine production. However, the role of IgM N-glycosylation has not been studied during acute...
10.
Allen A, Chung C, Worrell S, Nwaozo G, Madrid R, Mele A, et al.
Front Genome Ed
. 2023 May;
5:1101483.
PMID: 37124096
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 gene editing system has been shown to be effective at inhibiting human immunodeficiency virus type 1 (HIV-1). Studies have not consistently used...