Michael R Nonnemacher
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Explore the profile of Michael R Nonnemacher including associated specialties, affiliations and a list of published articles.
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78
Citations
1307
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Recent Articles
1.
Jones J, Gunderson C, Wigdahl B, Nonnemacher M
Epigenetics Chromatin
. 2025 Mar;
18(1):9.
PMID: 40055755
Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that infects multiple immune cell types and integrates into host cell DNA termed provirus. Under antiretroviral control, provirus in cells is...
2.
Garabet R, Dampier W, Tillman S, Malone K, Szep Z, Althoff A, et al.
J Neurovirol
. 2024 Jun;
30(4):423-433.
PMID: 38856821
Human immunodeficiency virus-associated neurocognitive disorders persist in the combination antiretroviral therapy era. CD4 nadir is a well-established predictor of cognition cross-sectionally, but its impact on longitudinal neurocognitive (NC) trajectories is...
3.
Gurrola T, Effah S, Sariyer I, Dampier W, Nonnemacher M, Wigdahl B
Front Microbiol
. 2024 May;
15():1393974.
PMID: 38812680
Human immunodeficiency virus type 1 (HIV-1) infection is well known as one of the most complex and difficult viral infections to cure. The difficulty in developing curative strategies arises in...
4.
Berman R, Dampier W, Nonnemacher M, Wigdahl B
Curr Opin HIV AIDS
. 2024 Mar;
19(3):150-156.
PMID: 38547339
Purpose Of Review: The leading gene editing strategy for a human immunodeficiency virus type 1 (HIV-1) cure involves the delivery of SaCas9 and two guide RNAs (gRNAs) in an adeno-associated...
5.
Duffy B, King K, Nepal B, Nonnemacher M, Kortagere S
Mol Neurobiol
. 2024 Mar;
61(10):8467-8480.
PMID: 38514527
HIV-1-associated neurocognitive disorders (HAND) are a major comorbidity of HIV-1 infection, marked by impairment of executive function varying in severity. HAND affects nearly half of people living with HIV (PLWH),...
6.
Dampier W, Berman R, Nonnemacher M, Wigdahl B
Front Genome Ed
. 2024 Jan;
5:1248982.
PMID: 38239625
The human immunodeficiency virus type 1 (HIV-1) pandemic has been slowed with the advent of anti-retroviral therapy (ART). However, ART is not a cure and as such has pushed the...
7.
Allen A, Chung C, Worrell S, Nwaozo G, Madrid R, Mele A, et al.
Front Genome Ed
. 2023 May;
5:1101483.
PMID: 37124096
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 gene editing system has been shown to be effective at inhibiting human immunodeficiency virus type 1 (HIV-1). Studies have not consistently used...
8.
Lawrence J, Schardien K, Wigdahl B, Nonnemacher M
Acta Neuropathol Commun
. 2023 Mar;
11(1):42.
PMID: 36915214
In the contexts of aging, injury, or neuroinflammation, activated microglia signaling with TNF-α, IL-1α, and C1q induces a neurotoxic astrocytic phenotype, classified as A1, A1-like, or neuroinflammatory reactive astrocytes. In...
9.
Mohamed H, Berman R, Connors J, Haddad E, Miller V, Nonnemacher M, et al.
Biomedicines
. 2023 Jan;
11(1).
PMID: 36672628
In people living with HIV-1 (PLWH), antiretroviral therapy (ART) eventually becomes necessary to suppress the emergence of human immunodeficiency virus type 1 (HIV-1) replication from latent reservoirs because HIV-1-specific immune...
10.
Marino J, Maubert M, Lawrence J, Wigdahl B, Nonnemacher M
Brain Sci
. 2022 Jul;
12(7).
PMID: 35884695
The blood-brain barrier (BBB) mediates cellular and molecular passage between the central nervous system (CNS) and peripheral circulation. Compromised BBB integrity has been linked to neurocognitive deficits in multiple diseases...