Methods in Molecular Biology
Overview
Methods in Molecular Biology is a renowned scientific journal that focuses on cutting-edge techniques and methodologies used in molecular biology research. It covers a wide range of topics, including DNA sequencing, gene expression analysis, protein purification, and cell culture techniques. With its comprehensive and detailed articles, this journal serves as an invaluable resource for researchers and scientists in the field of molecular biology.
Details
Details
Abbr.
Methods Mol Biol
Start
1984
End
Continuing
Frequency
Irregular
p-ISSN
1064-3745
e-ISSN
1940-6029
Country
United States
Language
English
Specialty
Molecular Biology
Metrics
Metrics
h-index / Ranks: 720
200
SJR / Ranks: 10393
399
CiteScore / Ranks: 10041
2.30
Recent Articles
11.
Lopez-Chiloeches M, Frisan T
Methods Mol Biol
. 2025 Mar;
2906:149-175.
PMID: 40082355
Understanding complex pathophysiological processes involves studying intercellular responses and phenotypes within the organ microenvironment, preserving the spatial tissue architecture. This chapter explores a practical and cost-effective method for combining techniques...
12.
Paulis M, Garbarino O, Faggioli F
Methods Mol Biol
. 2025 Mar;
2906:137-147.
PMID: 40082354
FISH (fluorescence in situ hybridization) is one of the most reliable cytogenetic techniques for detecting changes in DNA integrity, including copy number gains and losses as well as telomeric erosion....
13.
Hidmi O, Oster S, Shatleh D, Monin J, Aqeilan R
Methods Mol Biol
. 2025 Mar;
2906:113-136.
PMID: 40082353
DNA double-strand breaks (DSBs) are a major source of genomic instability. Physiological DSBs are naturally occurring breaks that happen during normal cellular processes. Unlike DNA breaks resulting from DNA damage...
14.
Logotheti S, Vasilopoulos S, Tremi I, Gkikoudi A, Fragkos M, Pavlopoulou A, et al.
Methods Mol Biol
. 2025 Mar;
2906:83-112.
PMID: 40082352
Senescence is a cellular stress response causing a stable exit from the cell cycle. Limitation of cell proliferation is accompanied by a variety of characteristic changes, including cellular and nuclear...
15.
Pangrazzi L, Martic I, Cavinato M, Weinberger B
Methods Mol Biol
. 2025 Mar;
2906:73-81.
PMID: 40082351
Cellular senescence is a biological process where somatic cells undergo irreversible growth arrest. One key marker of cellular senescence is senescence-associated β-galactosidase (SA-β-gal), an enzyme whose activity can be detected...
16.
Bakouros P, Archavli A, Kostopoulos I, Terpos E, Kastritis E, Dimopoulos M, et al.
Methods Mol Biol
. 2025 Mar;
2906:57-71.
PMID: 40082350
Cellular senescence, a stable cell cycle arrest induced by various stressors or DNA damage, plays a critical role in various aspects of human physiology, including embryonic development, wound healing, and...
17.
Mizi A, Tsitsianopoulos M, Papantonis A
Methods Mol Biol
. 2025 Mar;
2906:45-55.
PMID: 40082349
The dynamic character of senescence renders detection and selection of senescent cells challenging. One key feature of senescence is the alteration of chromatin features, and many methods for studying chromatin...
18.
Laouris P, Munoz-Espin D
Methods Mol Biol
. 2025 Mar;
2906:21-44.
PMID: 40082348
Cellular senescence plays a critical role in cancer, acting as both a tumor-suppressive and tumor-promoting mechanism. Senescent cells undergo stable cell-cycle arrest in response to various stressors, including DNA damage...
19.
Evangelou K, Belogiannis K, Pantelis P, Liaropoulos G, Skaltsas D, Sakellariou S, et al.
Methods Mol Biol
. 2025 Mar;
2906:1-20.
PMID: 40082347
Cellular senescence and aging are two distinct but overlapping entities that are both characterized by the intracellular accumulation of lipofuscin, the "dark" matter of the cell. Tissues like liver composed...
20.
Rodriguez-Bodero A, Bonifazi P, Tonnesen J, Encinas-Perez J
Methods Mol Biol
. 2025 Mar;
2899:367-388.
PMID: 40067635
Cultured organotypic hippocampal slices (hOTCs) have become increasingly popular as a model for studying brain function. This model offers significant advantages over traditional in vitro methods, as they allow the...