Yun Seong Jeong
Overview
Explore the profile of Yun Seong Jeong including associated specialties, affiliations and a list of published articles.
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20
Citations
394
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Recent Articles
11.
Kang S, Kim E, Hwang J, Shin J, Jeong Y, Yim S, et al.
Biochem Biophys Res Commun
. 2019 Feb;
511(1):185-191.
PMID: 30777332
High metabolic activity, reflected in increased glucose uptake, is one of the hallmarks of many cancers including breast cancer. However, not all cancers avidly take up glucose, suggesting heterogeneity in...
12.
Lee G, Jeong Y, Kim D, Kwak M, Koh J, Joo E, et al.
Exp Mol Med
. 2018 Nov;
50(11):1-12.
PMID: 30429453
Recent findings from The Cancer Genome Atlas project have provided a comprehensive map of genomic alterations that occur in hepatocellular carcinoma (HCC), including unexpected mutations in apolipoprotein B (APOB). We...
13.
Yim S, Shim J, Shin J, Jeong Y, Kang S, Kim S, et al.
Mol Cancer Res
. 2018 Aug;
16(11):1713-1723.
PMID: 30082483
Hepatocellular carcinoma (HCC) is a heterogeneous disease. Mouse models are commonly used as preclinical models to study hepatocarcinogenesis, but how well these models recapitulate molecular subtypes of human HCC is...
14.
Rezaeian A, Li C, Wu C, Zhang X, Delacerda J, You M, et al.
Nat Cell Biol
. 2016 Dec;
19(1):38-51.
PMID: 27918549
The understanding of how hypoxia stabilizes and activates HIF1α in the nucleus with related oncogenic signals could revolutionize targeted therapy for cancers. Here, we find that histone H2AX displays oncogenic...
15.
Chen J, Raju G, Jogunoori W, Menon V, Majumdar A, Chen J, et al.
PLoS One
. 2016 Apr;
11(4):e0153933.
PMID: 27100181
Mutational processes and signatures that drive early tumorigenesis are centrally important for early cancer prevention. Yet, to date, biomarkers and risk factors for polyps (adenomas) that inordinately and rapidly develop...
16.
Chen J, Yao Z, Chen J, Gi Y, Munoz N, Kundra S, et al.
J Clin Invest
. 2016 Jan;
126(2):527-42.
PMID: 26784546
Beckwith-Wiedemann syndrome (BWS) is a human stem cell disorder, and individuals with this disease have a substantially increased risk (~800-fold) of developing tumors. Epigenetic silencing of β2-spectrin (β2SP, encoded by...
17.
Yang W, Jin G, Li C, Jeong Y, Moten A, Xu D, et al.
Sci Signal
. 2013 Jan;
6(257):ra3.
PMID: 23300340
K63-linked ubiquitination of Akt is a posttranslational modification that plays a critical role in growth factor-mediated membrane recruitment and activation of Akt. Although E3 ligases involved in growth factor-induced ubiquitination...
18.
Wu J, Zhang X, Zhang L, Wu C, Rezaeian A, Chan C, et al.
Mol Cell
. 2012 Apr;
46(3):351-61.
PMID: 22464731
The Mre11/Rad50/NBS1 (MRN) complex is thought to be a critical sensor that detects damaged DNA and recruits ATM to DNA foci for activation. However, it remains to be established how...
19.
Wang J, Han F, Wu J, Lee S, Chan C, Wu C, et al.
Blood
. 2011 Sep;
118(20):5429-38.
PMID: 21931116
Although the maintenance of HSC quiescence and self-renewal are critical for controlling stem cell pool and transplantation efficiency, the mechanisms by which they are regulated remain largely unknown. Understanding the...
20.
Wu C, Kang H, Yang W, Wu J, Jeong Y, Wang J, et al.
J Biol Chem
. 2011 Jun;
286(35):30806-30815.
PMID: 21690091
DNA damage response is an important surveillance mechanism used to maintain the integrity of the human genome in response to genotoxic stress. Histone variant H2AX is a critical sensor that...