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Vytautas P Bindokas

Explore the profile of Vytautas P Bindokas including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1027
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Recent Articles
1.
Phillips E, Bindokas V, Jung D, Teamer J, Kitajewski J, Solaro R, et al.
Microcirculation . 2023 Aug; 30(7):e12826. PMID: 37605603
Objective: Three-dimensional (3D) microscopy and image data analysis are necessary for studying the morphology of cardiac lymphatic vessels (LyVs) and their association with other cell types. We aimed to develop...
2.
Wu Y, Moon H, Bindokas V, Phillips E, Park G, Lee S
Am J Respir Cell Mol Biol . 2023 Apr; 69(1):13-21. PMID: 37017484
Asthma is a chronic inflammatory airway disease driven by various infiltrating immune cell types into the lung. Optical microscopy has been used to study immune infiltrates in asthmatic lungs. Confocal...
3.
Phillips E, Bindokas V, Jung D, Teamer J, Kitajewski J, Solaro R, et al.
bioRxiv . 2023 Feb; PMID: 36778334
Objective: 3D microscopy and image data analysis are necessary for studying the morphology of cardiac lymphatic vessels (LyVs) and association with other cell types. We aimed to develop a methodology...
4.
Efimova E, Appelbe O, Ricco N, Lee S, Liu Y, Wolfgeher D, et al.
Mol Cancer Res . 2019 Mar; 17(6):1338-1350. PMID: 30885991
The metabolic reprogramming associated with characteristic increases in glucose and glutamine metabolism in advanced cancer is often ascribed to answering a higher demand for metabolic intermediates required for rapid tumor...
5.
Lee S, Bindokas V, Lingen M, Kron S
Lab Invest . 2018 Nov; 99(9):1400-1413. PMID: 30401959
Enumeration of tumor-infiltrating lymphocytes (TILs) in H&E stained tissue sections has demonstrated limited value in predicting immune responses to cancer immunotherapy, likely reflecting the diversity of cell types and immune...
6.
Lee S, Bindokas V, Kron S
Mol Cancer Ther . 2018 Oct; 18(1):213-226. PMID: 30322947
Macromolecular cancer drugs such as therapeutic antibodies and nanoparticles are well known to display slow extravasation and incomplete penetration into tumors, potentially protecting cancer cells from therapeutic effects. Conventional assays...
7.
Lee S, Bindokas V, Kron S
Sci Rep . 2017 Dec; 7(1):17031. PMID: 29208908
Recent developments in optical tissue clearing and microscopic imaging have advanced three-dimensional (3D) visualization of intact tissues and organs at high resolution. However, to expand applications to oncology, critical limitations...
8.
Wang J, Bindokas V, Skinner M, Emrick T, Marks J
Neurochem Int . 2017 Apr; 109:126-140. PMID: 28433663
Global brain ischemia can lead to widespread neuronal death and poor neurologic outcomes in patients. Despite detailed understanding of the cellular and molecular mechanisms mediating neuronal death following focal and...
9.
Zaborin A, Krezalek M, Hyoju S, DeFazio J, Setia N, Belogortseva N, et al.
Am J Physiol Gastrointest Liver Physiol . 2016 Dec; 312(2):G112-G122. PMID: 27979825
New & Noteworthy: This study provides novel insight into the process by which surgical injury places the intestinal epithelium at risk for colonization by pathogenic microbes and impairment of its...
10.
Arina A, Idel C, Hyjek E, Alegre M, Wang Y, Bindokas V, et al.
Proc Natl Acad Sci U S A . 2016 Jun; 113(27):7551-6. PMID: 27317748
Fibroblasts are common cell types in cancer stroma and lay down collagen required for survival and growth of cancer cells. Although some cancer therapy strategies target tumor fibroblasts, their origin...