Molecular Neurodegeneration
Overview
Molecular Neurodegeneration is a peer-reviewed scientific journal that focuses on the molecular mechanisms underlying neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's disease. It publishes cutting-edge research articles, reviews, and commentaries, providing valuable insights into the pathogenesis, diagnosis, and potential therapeutic strategies for these devastating disorders.
Details
Details
Abbr.
Mol Neurodegener
Publisher
Biomed Central
Start
2006
End
Continuing
e-ISSN
1750-1326
Country
United Kingdom
Language
English
Specialties
Neurology
Molecular Biology
Molecular Biology
Metrics
Metrics
h-index / Ranks: 2409
115
SJR / Ranks: 244
5205
CiteScore / Ranks: 209
25.00
JIF / Ranks: 224
15.1
Recent Articles
1.
Thal D, Poesen K, Vandenberghe R, De Meyer S
Mol Neurodegener
. 2025 Mar;
20(1):33.
PMID: 40087672
Alzheimer's disease (AD) is neuropathologically characterized by the extracellular deposition of the amyloid-β peptide (Aβ) and the intraneuronal accumulation of abnormal phosphorylated tau (τ)-protein (p-τ). Most frequently, these hallmark lesions...
2.
Morderer D, Wren M, Liu F, Kouri N, Maistrenko A, Khalil B, et al.
Mol Neurodegener
. 2025 Mar;
20(1):32.
PMID: 40082954
Background: Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mechanisms underlying the diversity of neuronal and...
3.
Sheth U, Oijerstedt L, Heckman M, White L, Heuer H, Lario Lago A, et al.
Mol Neurodegener
. 2025 Mar;
20(1):30.
PMID: 40075459
Background: Therapeutic development for frontotemporal dementia (FTD) is hindered by the lack of biomarkers that inform susceptibility/risk, prognosis, and the underlying causative pathology. Blood glial fibrillary acidic protein (GFAP) has...
4.
Serneels L, Sierksma A, Pasciuto E, Geric I, Nair A, Martinez-Muriana A, et al.
Mol Neurodegener
. 2025 Mar;
20(1):29.
PMID: 40069774
Background: Recent studies highlight the critical role of microglia in neurodegenerative disorders, and emphasize the need for humanized models to accurately study microglial responses. Human-mouse microglia xenotransplantation models are a...
5.
Hu M, Veldman M
Mol Neurodegener
. 2025 Mar;
20(1):28.
PMID: 40045384
Background: Axon regeneration within the mammalian central nervous system is extremely limited. In optic neuropathy conditions like glaucoma, the inability of retinal ganglion cell (RGC) axons to regenerate is a...
6.
Zhu R, Han R, Chen Y, Huang L, Liu T, Jiang J, et al.
Mol Neurodegener
. 2025 Mar;
20(1):27.
PMID: 40038816
Background: Parkinson's disease (PD) is a leading neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons, contributing to considerable disability worldwide. Current treatments offer only symptomatic relief, highlighting the...
7.
Sirerol-Piquer M, Perez-Villalba A, Duart-Abadia P, Belenguer G, Gomez-Pinedo U, Blasco-Chamarro L, et al.
Mol Neurodegener
. 2025 Mar;
20(1):26.
PMID: 40038767
Cytoplasmic alpha-synuclein (αSyn) aggregates are a typical feature of Parkinson's disease (PD). Extracellular insoluble αSyn can induce pathology in healthy neurons suggesting that PD neurodegeneration may spread through cell-to-cell transfer...
8.
Quan S, Fu X, Cai H, Ren Z, Xu Y, Jia L
Mol Neurodegener
. 2025 Mar;
20(1):25.
PMID: 40038765
The relationship between Alzheimer's disease (AD) and neuroimmunity has gradually begun to be unveiled. Emerging evidence indicates that cyclic GMP-AMP synthase (cGAS) acts as a cytosolic DNA sensor, recognizing cytosolic...
9.
Kim J, Yang S, Kim H, Vo D, Maeng H, Jo A, et al.
Mol Neurodegener
. 2025 Feb;
20(1):24.
PMID: 40022229
Background: The parkin-interacting substrate (PARIS, also known as ZNF746) is a transcriptional repressor, whose accumulation and phosphorylation play central pathological roles in Parkinson's disease (PD). PARIS-induced transcriptional repression of PGC-1α...
10.
Alosco M, Mejia Perez J, Culhane J, Shankar R, Nowinski C, Bureau S, et al.
Mol Neurodegener
. 2025 Feb;
20(1):23.
PMID: 39994806
Background: Molecular biomarkers of chronic traumatic encephalopathy (CTE) are lacking. We evaluated F-MK-6240 tau PET as a biomarker for CTE. Two studies were done: (1) H-MK-6240 autoradiography and an in-vitro...