Toshihide Kobayashi
Overview
Explore the profile of Toshihide Kobayashi including associated specialties, affiliations and a list of published articles.
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Articles
168
Citations
3814
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Recent Articles
1.
Eichler J, Huver S, Knorr C, Wendling C, Kobayashi T, Tomasetto C, et al.
Methods Mol Biol
. 2024 Dec;
2888:101-118.
PMID: 39699727
Cholesterol is a key component of biological membranes and, like many cellular lipids, is unevenly distributed among organelles. Disruptions in cholesterol trafficking are associated with various pathologies, including lysosomal lipid...
2.
Yamaji-Hasegawa A, Kobayashi T
Methods Mol Biol
. 2024 Dec;
2888:53-66.
PMID: 39699724
Maistero-2 is a novel, non-toxic cholesterol-binding protein derived from an edible mushroom Grifola frondosa mRNA. Maistero-2 specifically binds to lipid membranes containing 3-hydroxy sterols with a lower cholesterol concentration threshold...
3.
Abe M, Yanagawa M, Hiroshima M, Kobayashi T, Sako Y
Elife
. 2024 Nov;
13.
PMID: 39513999
Anionic lipid molecules, including phosphatidylinositol-4,5-bisphosphate (PI(4,5)P), are implicated in the regulation of epidermal growth factor receptor (EGFR). However, the role of the spatiotemporal dynamics of PI(4,5)P in the regulation of...
4.
Kaga C, Kakiyama S, Hokkyo A, Ogata Y, Shibata J, Nagahara T, et al.
Sci Rep
. 2024 Aug;
14(1):19387.
PMID: 39169196
Dogs diagnosed with chronic enteropathy (CE) or small-cell lymphoma (SCL) exhibit marked differences in faecal microbiota and organic acid profiles compared with healthy dogs, as well as immune abnormalities in...
5.
Mori T, Niki T, Uchida Y, Mukai K, Kuchitsu Y, Kishimoto T, et al.
Sci Rep
. 2024 Jul;
14(1):16872.
PMID: 39043900
Sphingomyelin (SM) is a major sphingolipid in mammalian cells. SM is enriched in the extracellular leaflet of the plasma membrane (PM). Besides this localization, recent electron microscopic and biochemical studies...
6.
Tomishige N, Takahashi K, Pollet B, Richert L, Mely Y, Kobayashi T
Methods Enzymol
. 2024 Jul;
700:217-234.
PMID: 38971601
Sphingomyelin is postulated to form clusters with glycosphingolipids, cholesterol and other sphingomyelin molecules in biomembranes through hydrophobic interaction and hydrogen bonds. These clusters form submicron size lipid domains. Proteins that...
7.
Hokkyo A, Kakiyama S, Shiwa Y, Kaga C, Kobayashi T, Nomoto K, et al.
Biosci Microbiota Food Health
. 2024 Jul;
43(3):204-212.
PMID: 38966045
Interest is growing in the relationship of the microbiota and intestinal environment with health in companion animals. Galacto-oligosaccharides (GOS), typical prebiotics, are expected to provide benefits in dogs. Previous studies...
8.
Kulma M, Sakanovic A, Bedina-Zavec A, Caserman S, Omersa N, Solinc G, et al.
Biochem Biophys Res Commun
. 2024 May;
716:149954.
PMID: 38704887
Membrane lipids and proteins form dynamic domains crucial for physiological and pathophysiological processes, including viral infection. Many plasma membrane proteins, residing within membrane domains enriched with cholesterol (CHOL) and sphingomyelin...
9.
Codini M, Fiorani F, Mandarano M, Cataldi S, Arcuri C, Mirarchi A, et al.
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139092
The role of sphingomyelin metabolism and vitamin C in cancer has been widely described with conflicting results ranging from a total absence of effect to possible preventive and/or protective effects....
10.
Tomishige N, Bin Nasim M, Murate M, Pollet B, Didier P, Godet J, et al.
Nat Commun
. 2023 Nov;
14(1):7353.
PMID: 37990014
Although the human immunodeficiency virus type 1 lipid envelope has been reported to be enriched with host cell sphingomyelin and cholesterol, the molecular mechanism of the enrichment is not well...