Toshihide Kobayashi
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Explore the profile of Toshihide Kobayashi including associated specialties, affiliations and a list of published articles.
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168
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3814
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Recent Articles
11.
Tannoo R, Richert L, Koschut D, Tomishige N, Treffert S, Kobayashi T, et al.
Biochim Biophys Acta Biomembr
. 2023 Oct;
1866(1):184236.
PMID: 37793560
Deregulation of the receptor tyrosine kinase MET/hepatocyte growth factor (HGF) pathway results in several pathological processes involved in tumor progression and metastasis. In a different context, MET can serve as...
12.
Kobayashi T, Tomishige N, Inaba T, Makino A, Murata M, Yamaji-Hasegawa A, et al.
Contact (Thousand Oaks)
. 2023 Jun;
4:25152564211042456.
PMID: 37366372
Sphingomyelin (SM) is a major sphingolipid in mammalian cells. Although SM is enriched in the outer leaflet of the cell plasma membrane, lipids are also observed in the inner leaflet...
13.
Yilmaz N, Panevska A, Tomishige N, Richert L, Mely Y, Sepcic K, et al.
J Biol Chem
. 2023 Jun;
299(8):104940.
PMID: 37343702
Ostreolysin A6 (OlyA6) is an oyster mushroom-derived membrane-binding protein that, upon recruitment of its partner protein, pleurotolysin B, forms a cytolytic membrane pore complex. OlyA6 itself is not cytolytic but...
14.
Murate M, Yokoyama N, Tomishige N, Richert L, Humbert N, Pollet B, et al.
Cell Mol Life Sci
. 2023 May;
80(6):167.
PMID: 37249637
Monosialoganglioside GM3 is the simplest ganglioside involved in various cellular signaling. Cell surface distribution of GM3 is thought to be crucial for the function of GM3, but little is known...
15.
Kobayashi T
Emerg Top Life Sci
. 2023 Jan;
7(1):31-45.
PMID: 36692108
Our knowledge on the asymmetric distribution of sphingomyelin (SM) in the plasma membrane is largely based on the biochemical analysis of erythrocytes using sphingomyelinase (SMase). However, recent studies showed that...
16.
Murate M, Kobayashi T
Methods Mol Biol
. 2022 Dec;
2613:189-202.
PMID: 36587080
Glycolipids are mainly distributed in the outer leaflet of the plasma membrane and are involved in cellular signaling by modulating the activity of cell surface receptor proteins. Glycolipids themselves also...
17.
Takahashi H, Hayakawa T, Makino A, Iwamoto K, Ito K, Sato S, et al.
Sci Rep
. 2022 Dec;
12(1):20803.
PMID: 36460753
Little is known about the molecular mechanisms of ceramide-mediated cellular signaling. We examined the effects of palmitoyl ceramide (C16-ceramide) and stearoyl ceramide (C18-ceramide) on the phase behavior of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)...
18.
Solinc G, Svigelj T, Omersa N, Snoj T, Pirc K, Znidarsic N, et al.
J Biol Chem
. 2022 Sep;
298(10):102455.
PMID: 36063994
Pore-forming proteins perforate lipid membranes and consequently affect their integrity and cell fitness. Therefore, it is not surprising that many of these proteins from bacteria, fungi, or certain animals act...
19.
Albi E, Arcuri C, Kobayashi T, Tomishige N, Cas M, Paroni R, et al.
Front Biosci (Landmark Ed)
. 2022 Aug;
27(8):247.
PMID: 36042186
Background: It has been established that sphingomyelin present human breast milk is useful for the brain maturation and cognitive development. At 10 days of breastfeeding the sphingomyelin content is double...
20.
Yamaji-Hasegawa A, Murate M, Inaba T, Dohmae N, Sato M, Fujimori F, et al.
Cell Mol Life Sci
. 2022 Jun;
79(6):324.
PMID: 35644822
We identified a mushroom-derived protein, maistero-2 that specifically binds 3-hydroxy sterol including cholesterol (Chol). Maistero-2 bound lipid mixture in Chol-dependent manner with a binding threshold of around 30%. Changing lipid...