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Tommy Martinsson

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Articles 94
Citations 2149
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Recent Articles
1.
Rahmqvist I, Engstrom E, Mellstrom E, Ibrahim R, Pujol-Calderon F, Dahlstrand Rudin A, et al.
Biomark Res . 2024 Nov; 12(1):148. PMID: 39593169
Circulating tumor DNA (ctDNA) has shown potential as a non-invasive tumor biomarker in neuroblastoma. Previous studies used generic assays for detection of selected predefined oncogenic variants as markers of ctDNA,...
2.
Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig M, et al.
EMBO J . 2024 Nov; 43(24):6310-6335. PMID: 39528654
Neuroblastoma (NB) is the most common extracranial childhood cancer, caused by the improper differentiation of developing trunk neural crest cells (tNCC) in the sympathetic nervous system. The N-methyladenosine (mA) epitranscriptomic...
3.
Park S, Fransson S, Sundquist F, Nilsson J, Gryback P, Wessman S, et al.
Front Oncol . 2024 Sep; 14:1408729. PMID: 39324010
In this case report, we present the treatment outcomes of the first patient enrolled in the LuDO-N trial. The patient is a 21-month-old girl diagnosed with high-risk neuroblastoma (NB) and...
4.
Suman M, Lofgren M, Fransson S, Yousuf J, Svensson J, Djos A, et al.
J Transl Med . 2024 Aug; 22(1):808. PMID: 39217334
Background: Neuroblastoma (NB) is a complex disease, and the current understanding of NB biology is limited. Deregulation in genomic imprinting is a common event in malignancy. Since imprinted genes play...
5.
Olsen T, Otte J, Mei S, Embaie B, Kameneva P, Cheng H, et al.
Mol Cancer . 2024 Aug; 23(1):180. PMID: 39217332
Background: Neuroblastoma (NB) is a heterogeneous embryonal malignancy and the deadliest tumor of infancy. It is a complex disease that can result in diverse clinical outcomes. In some children, tumors...
6.
Ek T, Ibrahim R, Vogt H, Georgantzi K, Trager C, Gaarder J, et al.
Cancer Res Commun . 2024 Aug; 4(9):2553-2564. PMID: 39177282
Significance: We present five patients with ALK-driven relapsed or refractory neuroblastoma treated with lorlatinib as monotherapy. All patients responded to treatment, and four of them were alive after 3 to...
7.
Djos A, Svensson J, Gaarder J, Umapathy G, Nilsson S, Ek T, et al.
Genes Chromosomes Cancer . 2024 Jul; 63(7):e23260. PMID: 39031441
Neuroblastoma (NB) is a heterogeneous childhood cancer with a slightly higher incidence in boys than girls, with the reason for this gender disparity unknown. Given the growing evidence for the...
8.
Maya-Gonzalez C, Delgado-Vega A, Taylan F, Lagerstedt Robinson K, Hansson L, Pal N, et al.
Am J Med Genet A . 2024 Jul; 194(12):e63812. PMID: 38990105
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder caused by pathogenic variants in FBN1, with a hitherto unknown association with cancer. Here, we present two females with MFS...
9.
Tesi B, Lagerstedt Robinson K, Abel F, Diaz De Stahl T, Orrsjo S, Poluha A, et al.
Lancet Reg Health Eur . 2024 May; 39:100881. PMID: 38803632
Background: Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable availability of germline testing, many children with ChiCaP might go...
10.
Vaid R, Thombare K, Mendez A, Burgos-Panadero R, Djos A, Jachimowicz D, et al.
Nucleic Acids Res . 2024 Jan; 52(5):2648-2671. PMID: 38180812
Telomerase-negative tumors maintain telomere length by alternative lengthening of telomeres (ALT), but the underlying mechanism behind ALT remains poorly understood. A proportion of aggressive neuroblastoma (NB), particularly relapsed tumors, are...